Campbell Biology in Focus
3rd Edition
ISBN: 9780134710679
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Rebecca Orr
Publisher: PEARSON
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Chapter 15.3, Problem 2CC
MAKE CONNECTIONS Inactivation of one of the X chromosomes in female mammals results in a Barr body (see Concept 12.2). Suggest a model for how the noncoding RNA described in Concept 12.2 (XIST RNA) functions to cause Barr body formation.
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MAKE CONNECTIONS Inactivation of one of the Xchromosomes in female mammals involves lncRNA calledXIST RNA, mentioned in this section and in Concept 15.2.Describe transcription and binding of XIST RNA, thensuggest a model for how it initiates Barr body formation.
Alignment of protein sequences from the HOx gene family identifies a highly conserved domain in the C-terminal part of the protein that is a
domain (one acronym and one word). Although Hox genes have important roles during embryogenesis and tissue
(one word) that are rich in the bases
(one word each). To ensure high affinity binding to
and
differentiation, the different HOX proteins bind to very similar DNA
(one acronym)
(one word). the HOX proteins form complexes with
(two words).
and specific regulation of target
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Chapter 15 Solutions
Campbell Biology in Focus
Ch. 15.1 - How does binding of the trp corepressor to its...Ch. 15.1 - Describe the binding of RNA polymerase,...Ch. 15.1 - WHAT IF? A certain mutation in E. coli changes the...Ch. 15.2 - Prob. 1CCCh. 15.2 - Compare the roles of general and specific...Ch. 15.2 - Prob. 3CCCh. 15.3 - WHAT IF? Suppose the mRNA being degraded in Figure...Ch. 15.3 - MAKE CONNECTIONS Inactivation of one of the X...Ch. 15.4 - Prob. 1CCCh. 15.4 - WHAT IF? Study the microarray in Figure 15.17. If...
Ch. 15 - If a particular operon encodes enzymes for making...Ch. 15 - The functioning of enhancers is an example of A. a...Ch. 15 - Which of the following is an example of...Ch. 15 - Prob. 4TYUCh. 15 - Prob. 5TYUCh. 15 - Which of the following would not be true of cDNA...Ch. 15 - Prob. 7TYUCh. 15 - SCIENTIFIC INQUIRY Imagine you want to study one...Ch. 15 - FOCUS ON EVOLUTION DNA sequences can act as tape...Ch. 15 - FOCUS ON INTERACTIONS In a short essay (100150...Ch. 15 - Prob. 11TYU
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- Discuss Concepts The genome of the yeast Saccharomyces cerevisiae is only about 0.4% the size of the human genome, yet itcontains about 30% as many genes as are in the human genome. Given that, which of the features of the human genome would you expect to find many fewer of in the yeast genome?arrow_forwardDiscuss Concepts Why do you suppose cells evolved internal response mechanisms using molecules that bind GTP instead of ATP?arrow_forwardDosage compensation is critical for organisms with sex chromosomes to equilibrate gene expression. The role of long non-coding RNAs has been shown to play an important role in affecting the decision to carry out X chromosome inactivation during dosage compensation in mammals. Q9a) How can a long non-coding RNA affect the decision to keep an X-chromosome active in female mammals? Q9b) How can a long non-coding RNA initiate the steps to silence the chromosome to be inactivated? Q9c) Explain which long non-coding RNA is responsible for the various steps to silence the inactive X and describe how its function leads to changes in the chromatin that are incompatible with active transcription off the inactive Xarrow_forward
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- . One way to determine where inside a cell a protein(protein X) normally localizes is to generate a reportergene construct containing: (i) the gene X regulatoryregion and coding sequences, and (ii) coding sequencesfor GFP fused in frame to the 3′ end of the gene Xcoding sequences just before the stop codon. A mousecontaining such a transgene will express a hybrid protein X-GFP only in those cells in which gene X is normally expressed.a. The gene X-GFP fusion gene described could begenerated by knocking in GFP coding sequencesinstead of by random insertion of a transgene.Diagram the knockin construct you could use forthis purpose.b. What might the advantage be of the knockin strategy versus the transgene strategy?arrow_forwardPlz answer correctly asaparrow_forwardExamine the network motifs in Figure Q8–5.Decide which ones are negative feedback loops and whichare positive. Explain your reasoning.arrow_forward
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