Foundations in Microbiology
10th Edition
ISBN: 9781259705212
Author: Kathleen Park Talaro, Barry Chess Instructor
Publisher: McGraw-Hill Education
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Question
Chapter 15.3, Problem 14CYP
Summary Introduction
To identify:
Traces of immune response system, beginning with the entry of a T- cell – dependent antigen, antigen processing, presentation, the co-operative response among the macrophage and lymphocytes and the reactions of activated B cells.
Introduction:
Antigens introduced intravenously become localized in the liver, spleen, bone marrow, kidney, and lung. If introduced by some other route, antigens are carried in lymphatic fluid and concentrated by the lymph nodes.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 15 Solutions
Foundations in Microbiology
Ch. 15.1 - Summarize the general features of adaptive,...Ch. 15.1 - Prob. 2ELOCh. 15.1 - Prob. 3ELOCh. 15.1 - Prob. 4ELOCh. 15.1 - Describe the major events in the origin of...Ch. 15.1 - Describe the development of antigen receptors on...Ch. 15.1 - Prob. 7ELOCh. 15.1 - Discuss what is meant by immunocompetence, immune...Ch. 15.1 - What function do receptors play in specific immune...Ch. 15.1 - Prob. 3CYP
Ch. 15.1 - Explain the clonal selection theory of receptor...Ch. 15.1 - Why must the body develop tolerance to seit?Ch. 15.1 - Prob. 6CYPCh. 15.1 - What is happening during lymphocyte maturation?Ch. 15.1 - Prob. 8CYPCh. 15.2 - Explain the characteristics of antigens, the...Ch. 15.2 - Discuss the main categories of antigens, based on...Ch. 15.2 - What are antigens, immunogens, and epitopes, and...Ch. 15.2 - How do foreignness, size, and complexity...Ch. 15.2 - Compare five unique types of antigens, and explain...Ch. 15.3 - Describe the cooperative interactions between...Ch. 15.3 - Discuss the actions of interleukins in the early...Ch. 15.3 - Prob. 12ELOCh. 15.3 - Prob. 13ELOCh. 15.3 - Prob. 14ELOCh. 15.3 - Prob. 15ELOCh. 15.3 - Prob. 12CYPCh. 15.3 - Prob. 13CYPCh. 15.3 - Prob. 14CYPCh. 15.3 - Prob. 15CYPCh. 15.3 - Prob. 16CYPCh. 15.3 - Prob. 17CYPCh. 15.3 - Prob. 18CYPCh. 15.3 - Discuss how superantigens are different from other...Ch. 15.4 - Prob. 16ELOCh. 15.4 - Prob. 17ELOCh. 15.4 - Prob. 18ELOCh. 15.4 - Prob. 19ELOCh. 15.4 - Prob. 20CYPCh. 15.4 - What are the functions of plasma cells, clonal...Ch. 15.4 - Prob. 22CYPCh. 15.4 - Prob. 23CYPCh. 15.4 - Describe the attachment of antibodies to antigens....Ch. 15.4 - Prob. 25CYPCh. 15.4 - Prob. 26CYPCh. 15.4 - What causes the latent period and the anamnestic...Ch. 15.5 - Prob. 20ELOCh. 15.5 - Differentiate between natural and artificial...Ch. 15.5 - Expand on the four combinations of the defining...Ch. 15.5 - Prob. 28CYPCh. 15.5 - Name at least two major ways in which natural and...Ch. 15.5 - Prob. 30CYPCh. 15.6 - Explain the purposes of immunotherapy and...Ch. 15.6 - Describe the sources and uses of artificial...Ch. 15.6 - Discuss which factors are involved in vaccine...Ch. 15.6 - Identify the major categories of vaccine antigens,...Ch. 15.6 - Prob. 27ELOCh. 15.6 - Describe the preparation of killed vaccines; live,...Ch. 15.6 - Prob. 32CYPCh. 15.6 - Prob. 33CYPCh. 15.6 - Prob. 34CYPCh. 15.L1 - Which of these characteristics is not a major...Ch. 15.L1 - Prob. 2MCQCh. 15.L1 - In humans, B cells mature in the _____________ and...Ch. 15.L1 - Small, simple molecules are_________antigens. a....Ch. 15.L1 - Which type of cell actually secretes antibodies?...Ch. 15.L1 - CD4 cells are ________ cells and CD8 cells are...Ch. 15.L1 - Prob. 7MCQCh. 15.L1 - Prob. 8MCQCh. 15.L1 - Prob. 9MCQCh. 15.L1 - Prob. 10MCQCh. 15.L1 - Prob. 11MCQCh. 15.L1 - Prob. 12MCQCh. 15.L1 - Prob. 13MCQCh. 15.L1 - A living microbe with reduced virulence that is...Ch. 15.L1 - A vaccine that contains parts of viruses is called...Ch. 15.L1 - Prob. 16MCQCh. 15.L1 - Prob. 17MCQCh. 15.L1 - Prob. 18MCQCh. 15.L1 - Prob. 19MCQCh. 15.L1 - Prob. 20MCQCh. 15.L1 - Prob. 1CSRCh. 15.L1 - Prob. 2CSRCh. 15.L1 - Prob. 3CSRCh. 15.L1 - Using words and arrows, complete a flow outline of...Ch. 15.L1 - Prob. 2WCCh. 15.L1 - Prob. 3WCCh. 15.L1 - Prob. 4WCCh. 15.L1 - Prob. 5WCCh. 15.L1 - Combine information on the functions of different...Ch. 15.L2 - Prob. 1CTCh. 15.L2 - Prob. 2CTCh. 15.L2 - Double-stranded DNA is a large, complex molecule,...Ch. 15.L2 - Prob. 4CTCh. 15.L2 - Describe the relationship between an antitoxin, a...Ch. 15.L2 - Prob. 6CTCh. 15.L2 - Prob. 7CTCh. 15.L2 - Prob. 8CTCh. 15.L2 - Prob. 9CTCh. 15.L2 - Prob. 1VCCh. 15.L2 - Examine figure 6.6c and determine which components...
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