Nester's Microbiology: A Human Perspective
Nester's Microbiology: A Human Perspective
9th Edition
ISBN: 9781259709999
Author: Denise G. Anderson Lecturer, Sarah Salm, Deborah Allen
Publisher: McGraw-Hill Education
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Chapter 15, Problem 6SA
Summary Introduction

To review:

The Clonal selection and clonal expansion processes during an immune response in the body.

Introduction:

Clonal selection is a critical operating principle of adaptive immune response. Here, the newly generated B-cells (lymphocytes maturing in the bone marrow) or the naïve B-cells forma range of antibodies with a unique antigen binding site (Fab). When the body encounters an antigen, the B-cells that can make the appropriate antibodies interacts with the antigen. The multiplication of only those specific cells begins, that is called clonal expansion.

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