Biochemistry
Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
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Chapter 15, Problem 5P
Interpretation Introduction

To determine:

The value of Y (the fractional saturation of hemoglobin with O2) and comparison for Ylungs= Ycapillariesfor n =2.8 versus n = 1 and the effect of cooperative O2binding on oxygen delivery by hemoglobin.

Introduction:

Using the equation:

  Y1Y=[pO2]P50n

For P50= 26 torr, n = 2.8, calculate Y at pO2= 100 torr and at pO2= 40 torr and then if the n =1 (No cooperativity). Discuss the efficiency in cooperative oxygen delivery.

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