Biochemistry
Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
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Chapter 15, Problem 1P

Answers to all problems are at the end of this book. Detailed solutions are available in the Student Solutions Manual, Study Guide, and Problems Book.

General Controls Over Enzyme Activity List six general ways in which enzyme activity is controlled.

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Interpretation Introduction

To list:

Six general ways in which enzyme activity is controlled.

Introduction:

The number of moles of substrate converted per unit time is said to be the enzyme activity.

Explanation of Solution

Enzyme activity is controlled through various mechanisms in the cell. They are listed as:

  1. With the enzymatic reaction, substrate is converted to product. So, product accumulates as the reaction reaches the equilibrium state.
  2. Presence of substrate and cofactors
  3. Modifying enzymes or activator enzymes activate or inhibit the enzyme action
  4. Amount of available enzyme in the cell is regulated
  5. Allosteric regulation
  6. Interaction with modular proteins regulates enzyme activity
  7. Proteolysis
  8. Presence of isozymes

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