Human Heredity: Principles and Issues (MindTap Course List)
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Chapter 15, Problem 3QP
Summary Introduction

To determine: The difficulties faced by geneticists in mapping the human genes by using pedigrees.

Introduction: The pedigree analysis is the basic method in human genetics. It is an important tool to study human inherited diseases. The pedigree analysis is mostly used to examine the mode of the inheritance of different genetic diseases.

Summary Introduction

To determine: The significance of recombinant DNA technology in mapping the human genes.

Introduction: Recombinant DNA technology significantly changed the gene-mapping method. Positional cloning is a recombinant DNA-based method that is used for mapping and the cloning of genes. In this method, prior information about the gene product or its function is not required.

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Before the advent of recombinant DNA technology, why was it so diffcult for geneticists to map human genes using pedigrees? How did recombinant DNA technology help move things forward?
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