
Concept explainers
To tell:
Why the mucous membrane barriers and skin of the body are not the significant factors in your resistance to infection by hyper thermophiles?
Introduction:
The skin and mucous membrane are the most effective barriers to the infection. The surface of the skin inhibits the growth of the microorganism because of low pH and moisture. The innate immune response against the pathogen includes the skin and mucus and the skin is composed of epidermis and dermis. There are several layers which are tightly packed in cells. Epidermal dendritic cells have phagocytized the pathogens. However, the mucous membrane has two layers of epithelial cells and dendritic cells. Epithelial cells are tightly packed which prevents the entry of pathogens. The first line of defense in the body acts against the pathogens by antimicrobial peptides which are produced by the skin and mucous membrane eliminates the microbes.

Explanation of Solution
Hyper thermophile is the organism which lives in an extremely hot environmentof 60°C to 80°C. The human body is naturally resistant to the hyper thermophiles infection because the body temperature of humans is low. It is very difficult for the growth of hyper thermophiles.
Hence, the skin and mucous barrier are not a significant factor for protecting the body from the infection by hyper thermophiles.
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