If a point mutation occurs within a human egg cell genome that changes an A to a T, what is the most likely effect of this mutation on the phenotype of an offspring that develops from this mutated egg?

Question

Want to see more full solutions like this?

Answer 1

Textbook Question

Chapter 15, Problem 1NST

If a point mutation occurs within a human egg cell genome that changes an A to a T, what is the most likely effect of this mutation on the phenotype of an offspring that develops from this mutated egg?

Expert Solution & Answer

Summary Introduction

To determine: The phenotypic effect of a point mutation in an offspring.

Introduction: A change of one base pair to another in a DNA molecule is called point mutation. A change of one nucleotide of a triplet within a protein-coding portion of a gene results in a new triplet that codes for a different amino acid in the protein product.

Explanation of Solution

The phenotypic effect of any base change is dependent on a number of factors. These factors are as follows:

Location of the base pair in coding or noncoding region.
Interaction with other base sequences in the genome.
Base pair potential in dominance or recessiveness.

If a base change is located in a noncoding region, there may be no influence on the phenotype. Some noncoding region serves regulatory functions. The mutations that influence transcription levels, polyA addition, splicing, and translation can affect phenotype.

If a mutation occurs in a coding region that acts as a full recessive, there should be no influence on the phenotype. If a mutant gene acts as a dominant, then there would be an influence on the phenotype.

Conclusion

Thus, the phenotypic effect of point mutation depends on the location of the base pair, interaction with base pair, and potential of base pair.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Students have asked these similar questions

unu grow because auxin is still produced in the tip to Another of Boysen and Jensen's experiments included the use of mica, explain why one of the shoots was able to show phototropism and the other was not. Mica Wafer Ligh c. They then t but this time permeable n shoot. Why phototropis Light Mica Wafer Coleoptile tips Tips removed: agar Explain why the shoo direction after the ag the cut shoot, even t

Discussion entries must be at least 250 words to fulfill the assignment requirements. You must complete your entry before you will be able to see the responses of other students. Responses to other students are encouraged but not required. Grading for discussion entries will be based on application of course concepts, proper grammar, and correct punctuation. Read one the attached article and explore the Human Development Index (https://hdr.undp.org/data-center/human-development-index#/indicies/HDI). In your opinion, is the Human Development Index a good measure of the well- being of the people of a nation? Are the items measured in the HDI valid and relevant in the modern global economy? How are they related to the political economy of a nation? The attached articles propose some alternative measures of well-being. In your opinion, are there other measures of well-being that might be better alternatives to the items in the current HDI?

A patient visits her doctor with symptoms typical of a bladder infection. She is immediately prescribed an 800 mgdose of antibiotic (bioavailability = 1/2, t½ = 12 h). The corresponding plasma concentration of drug is found to be 96 micrograms/ml. What is the volume of distribution of this drug? Please round to the nearest liter.

Answer 2

Textbook Question

Chapter 15, Problem 1NST

If a point mutation occurs within a human egg cell genome that changes an A to a T, what is the most likely effect of this mutation on the phenotype of an offspring that develops from this mutated egg?

Expert Solution & Answer

Summary Introduction

To determine: The phenotypic effect of a point mutation in an offspring.

Introduction: A change of one base pair to another in a DNA molecule is called point mutation. A change of one nucleotide of a triplet within a protein-coding portion of a gene results in a new triplet that codes for a different amino acid in the protein product.

Explanation of Solution

The phenotypic effect of any base change is dependent on a number of factors. These factors are as follows:

Location of the base pair in coding or noncoding region.
Interaction with other base sequences in the genome.
Base pair potential in dominance or recessiveness.

If a base change is located in a noncoding region, there may be no influence on the phenotype. Some noncoding region serves regulatory functions. The mutations that influence transcription levels, polyA addition, splicing, and translation can affect phenotype.

If a mutation occurs in a coding region that acts as a full recessive, there should be no influence on the phenotype. If a mutant gene acts as a dominant, then there would be an influence on the phenotype.

Conclusion

Thus, the phenotypic effect of point mutation depends on the location of the base pair, interaction with base pair, and potential of base pair.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 3

Textbook Question

Chapter 15, Problem 1NST

If a point mutation occurs within a human egg cell genome that changes an A to a T, what is the most likely effect of this mutation on the phenotype of an offspring that develops from this mutated egg?

Expert Solution & Answer

Summary Introduction

To determine: The phenotypic effect of a point mutation in an offspring.

Introduction: A change of one base pair to another in a DNA molecule is called point mutation. A change of one nucleotide of a triplet within a protein-coding portion of a gene results in a new triplet that codes for a different amino acid in the protein product.

Explanation of Solution

The phenotypic effect of any base change is dependent on a number of factors. These factors are as follows:

Location of the base pair in coding or noncoding region.
Interaction with other base sequences in the genome.
Base pair potential in dominance or recessiveness.

If a base change is located in a noncoding region, there may be no influence on the phenotype. Some noncoding region serves regulatory functions. The mutations that influence transcription levels, polyA addition, splicing, and translation can affect phenotype.

If a mutation occurs in a coding region that acts as a full recessive, there should be no influence on the phenotype. If a mutant gene acts as a dominant, then there would be an influence on the phenotype.

Conclusion

Thus, the phenotypic effect of point mutation depends on the location of the base pair, interaction with base pair, and potential of base pair.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 4

Textbook Question

Chapter 15, Problem 1NST

If a point mutation occurs within a human egg cell genome that changes an A to a T, what is the most likely effect of this mutation on the phenotype of an offspring that develops from this mutated egg?

Expert Solution & Answer

Summary Introduction

To determine: The phenotypic effect of a point mutation in an offspring.

Introduction: A change of one base pair to another in a DNA molecule is called point mutation. A change of one nucleotide of a triplet within a protein-coding portion of a gene results in a new triplet that codes for a different amino acid in the protein product.

Explanation of Solution

The phenotypic effect of any base change is dependent on a number of factors. These factors are as follows:

Location of the base pair in coding or noncoding region.
Interaction with other base sequences in the genome.
Base pair potential in dominance or recessiveness.

If a base change is located in a noncoding region, there may be no influence on the phenotype. Some noncoding region serves regulatory functions. The mutations that influence transcription levels, polyA addition, splicing, and translation can affect phenotype.

If a mutation occurs in a coding region that acts as a full recessive, there should be no influence on the phenotype. If a mutant gene acts as a dominant, then there would be an influence on the phenotype.

Conclusion

Thus, the phenotypic effect of point mutation depends on the location of the base pair, interaction with base pair, and potential of base pair.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 5

Textbook Question

Answer 6

Textbook Question

Answer 7

Expert Solution & Answer

Summary Introduction

To determine: The phenotypic effect of a point mutation in an offspring.

Introduction: A change of one base pair to another in a DNA molecule is called point mutation. A change of one nucleotide of a triplet within a protein-coding portion of a gene results in a new triplet that codes for a different amino acid in the protein product.

Explanation of Solution

The phenotypic effect of any base change is dependent on a number of factors. These factors are as follows:

Location of the base pair in coding or noncoding region.
Interaction with other base sequences in the genome.
Base pair potential in dominance or recessiveness.

If a base change is located in a noncoding region, there may be no influence on the phenotype. Some noncoding region serves regulatory functions. The mutations that influence transcription levels, polyA addition, splicing, and translation can affect phenotype.

If a mutation occurs in a coding region that acts as a full recessive, there should be no influence on the phenotype. If a mutant gene acts as a dominant, then there would be an influence on the phenotype.

Conclusion

Thus, the phenotypic effect of point mutation depends on the location of the base pair, interaction with base pair, and potential of base pair.

Answer 8

Expert Solution & Answer

Summary Introduction

To determine: The phenotypic effect of a point mutation in an offspring.

Introduction: A change of one base pair to another in a DNA molecule is called point mutation. A change of one nucleotide of a triplet within a protein-coding portion of a gene results in a new triplet that codes for a different amino acid in the protein product.

Explanation of Solution

The phenotypic effect of any base change is dependent on a number of factors. These factors are as follows:

Location of the base pair in coding or noncoding region.
Interaction with other base sequences in the genome.
Base pair potential in dominance or recessiveness.

If a base change is located in a noncoding region, there may be no influence on the phenotype. Some noncoding region serves regulatory functions. The mutations that influence transcription levels, polyA addition, splicing, and translation can affect phenotype.

If a mutation occurs in a coding region that acts as a full recessive, there should be no influence on the phenotype. If a mutant gene acts as a dominant, then there would be an influence on the phenotype.

Conclusion

Thus, the phenotypic effect of point mutation depends on the location of the base pair, interaction with base pair, and potential of base pair.

Answer 9

Expert Solution & Answer

Answer 10

Expert Solution & Answer

Answer 11

Summary Introduction

To determine: The phenotypic effect of a point mutation in an offspring.

Introduction: A change of one base pair to another in a DNA molecule is called point mutation. A change of one nucleotide of a triplet within a protein-coding portion of a gene results in a new triplet that codes for a different amino acid in the protein product.

Answer 12

Explanation of Solution

The phenotypic effect of any base change is dependent on a number of factors. These factors are as follows:

Location of the base pair in coding or noncoding region.
Interaction with other base sequences in the genome.
Base pair potential in dominance or recessiveness.

If a base change is located in a noncoding region, there may be no influence on the phenotype. Some noncoding region serves regulatory functions. The mutations that influence transcription levels, polyA addition, splicing, and translation can affect phenotype.

If a mutation occurs in a coding region that acts as a full recessive, there should be no influence on the phenotype. If a mutant gene acts as a dominant, then there would be an influence on the phenotype.