EBK CONCEPTS OF GENETICS
EBK CONCEPTS OF GENETICS
12th Edition
ISBN: 9780134818979
Author: Killian
Publisher: YUZU
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Chapter 15, Problem 16PDQ

A significant number of mutations in the HBB gene that cause human β-thalassemia occur within introns or in upstream non-coding sequences. Explain why mutations in these regions often lead to severe disease, although they may not directly alter the coding regions of the gene.

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EBK CONCEPTS OF GENETICS

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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY