How does the absence of proofreading ability for RNA polymerase affect the rate of error in the transcription process in comparison with DNA replication . Introduction: To convert genotype to phenotype , the conversion of information saved in the DNA to proteins is required. The central dogma describes the flow of information is one direction (DNA to RNA, and RNA to proteins). The flow of information from DNA to RNA is referred to as transcription, while the flow of information from RNA to protein is referred to as translation.

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Chapter 15, Problem 1IQ

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To describe: How does the absence of proofreading ability for RNA polymerase affect the rate of error in the transcription process in comparison with DNA replication.

Introduction: To convert genotype to phenotype, the conversion of information saved in the DNA to proteins is required. The central dogma describes the flow of information is one direction (DNA to RNA, and RNA to proteins). The flow of information from DNA to RNA is referred to as transcription, while the flow of information from RNA to protein is referred to as translation.

Summary Introduction

To describe: Why it is believed that proofreading capacity for DNA polymerase is more essential than for RNA polymerase.

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19. On the diagram below a. Label the three pictures as: DNA; polypeptide; or RNA. b. Label the arrows as: translation or transcription/RNA processing. c. Add the following details to the diagram. Promoter region TATA box Transcription start site Transcription terminator Intron (A,B,C,D) Exons (1,2,3,4,5) Splice sites 5' cap 5' UTR (untranslated region) 3' poly A tail 3' UTR (untranslated region) Translational start (AUG) Translational stop (UGA, UAG, or UAA) N and C ends of polypeptide 0000

Match the letter labels in the figure below to the terms. Some letter labels are not used. MNNNNNNIN M C B A M D F E H K G 8

The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions. 1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction? 2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe: a) What molecule do you recommend for the trial. Why? b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for? 3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale. 4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale. Mutation 1 Mutation 2

Answer 2

Question

Chapter 15, Problem 1IQ

Summary Introduction

To describe: How does the absence of proofreading ability for RNA polymerase affect the rate of error in the transcription process in comparison with DNA replication.

Introduction: To convert genotype to phenotype, the conversion of information saved in the DNA to proteins is required. The central dogma describes the flow of information is one direction (DNA to RNA, and RNA to proteins). The flow of information from DNA to RNA is referred to as transcription, while the flow of information from RNA to protein is referred to as translation.

Summary Introduction

To describe: Why it is believed that proofreading capacity for DNA polymerase is more essential than for RNA polymerase.

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Answer 3

Question

Chapter 15, Problem 1IQ

Summary Introduction

To describe: How does the absence of proofreading ability for RNA polymerase affect the rate of error in the transcription process in comparison with DNA replication.

Introduction: To convert genotype to phenotype, the conversion of information saved in the DNA to proteins is required. The central dogma describes the flow of information is one direction (DNA to RNA, and RNA to proteins). The flow of information from DNA to RNA is referred to as transcription, while the flow of information from RNA to protein is referred to as translation.

Summary Introduction

To describe: Why it is believed that proofreading capacity for DNA polymerase is more essential than for RNA polymerase.

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Answer 4

Question

Chapter 15, Problem 1IQ

Summary Introduction

To describe: How does the absence of proofreading ability for RNA polymerase affect the rate of error in the transcription process in comparison with DNA replication.

Introduction: To convert genotype to phenotype, the conversion of information saved in the DNA to proteins is required. The central dogma describes the flow of information is one direction (DNA to RNA, and RNA to proteins). The flow of information from DNA to RNA is referred to as transcription, while the flow of information from RNA to protein is referred to as translation.

Summary Introduction

To describe: Why it is believed that proofreading capacity for DNA polymerase is more essential than for RNA polymerase.

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Answer 5

Chapter 15, Problem 1IQ

Summary Introduction

To describe: How does the absence of proofreading ability for RNA polymerase affect the rate of error in the transcription process in comparison with DNA replication.

Introduction: To convert genotype to phenotype, the conversion of information saved in the DNA to proteins is required. The central dogma describes the flow of information is one direction (DNA to RNA, and RNA to proteins). The flow of information from DNA to RNA is referred to as transcription, while the flow of information from RNA to protein is referred to as translation.

Summary Introduction

To describe: Why it is believed that proofreading capacity for DNA polymerase is more essential than for RNA polymerase.

Answer 6

Chapter 15, Problem 1IQ

Summary Introduction

To describe: How does the absence of proofreading ability for RNA polymerase affect the rate of error in the transcription process in comparison with DNA replication.

Introduction: To convert genotype to phenotype, the conversion of information saved in the DNA to proteins is required. The central dogma describes the flow of information is one direction (DNA to RNA, and RNA to proteins). The flow of information from DNA to RNA is referred to as transcription, while the flow of information from RNA to protein is referred to as translation.

Answer 7

Chapter 15, Problem 1IQ

Summary Introduction

To describe: How does the absence of proofreading ability for RNA polymerase affect the rate of error in the transcription process in comparison with DNA replication.

Introduction: To convert genotype to phenotype, the conversion of information saved in the DNA to proteins is required. The central dogma describes the flow of information is one direction (DNA to RNA, and RNA to proteins). The flow of information from DNA to RNA is referred to as transcription, while the flow of information from RNA to protein is referred to as translation.

Answer 8

Summary Introduction

To describe: Why it is believed that proofreading capacity for DNA polymerase is more essential than for RNA polymerase.

Answer 9

Summary Introduction

To describe: Why it is believed that proofreading capacity for DNA polymerase is more essential than for RNA polymerase.

Answer 10

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Answer 13

Ch. 15.1 - Prob. 1LO Ch. 15.1 - Prob. 2LO Ch. 15.1 - List the roles played by RNA in gene expression.Ch. 15.2 - Prob. 1LO Ch. 15.2 - Describe the characteristics of the genetic code.Ch. 15.2 - Prob. 3LO Ch. 15.3 - Prob. 1LO Ch. 15.3 - Differentiate among initiation, elongation, and...Ch. 15.3 - Prob. 3LO Ch. 15.4 - Prob. 1LO

Solution Summary: The author explains how the absence of proofreading capacity for RNA polymerase affects the rate of error in the transcription process.

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To describe: Why it is believed that proofreading capacity for DNA polymerase is more essential than for RNA polymerase.

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