BROOKER BIOLOGY
5th Edition
ISBN: 9781307656152
Author: BROOKER
Publisher: MCG/CREATE
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Chapter 14, Problem 9TY
Summary Introduction
Introduction: Iron is an important cofactor for various types of cellular enzymes but is toxic at elevated concentrations. For the prevention of toxic effects, some proteins are synthesized in mammalian cells, which reduce toxic level of proteins.
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Suppose hemoglobin is inhibited at the post-translational level. This means is it regulated at the _____
Select one:
a.
DNA level and mRNA will not be made
b.
tRNA level and protein will not be made
c.
mRNA level and the protein will not be made
d.
protein level and it will be inactive
e.
precursor mRNA level and mature mRNA will not be made
The primary function of 5' & 3' end mRNA modification is:
a. To ensure that phosphorylation of the nucleotides
b. Protection from nucleolytic degradation
c. Assurance of end joining during nuclear export.
d. To activate removal of introns
e. All of the above.
Define (whether post-transcriptional, post-translational, transcription) and describe the regulation of the Ferretin mRNA in the diagram below.
Chapter 14 Solutions
BROOKER BIOLOGY
Ch. 14.1 - Prob. 1CCCh. 14.2 - Which genes are under the control of the lac...Ch. 14.2 - With regard to regulatory proteins and small...Ch. 14.2 - What were the key observations made by Jacob,...Ch. 14.2 - CoreSKILL What was the eventual hypothesis...Ch. 14.2 - Prob. 3EQCh. 14.2 - Core Skill: Connections Look back at Fig 9.12....Ch. 14.2 - What are the advantages of having both an...Ch. 14.2 - Prob. 2CSCh. 14.3 - Prob. 1CC
Ch. 14.4 - What are the two opposing effects that histone...Ch. 14.4 - Prob. 1CSCh. 14.5 - Prob. 1CCCh. 14.5 - Prob. 2CCCh. 14 - Prob. 1TYCh. 14 - Prob. 2TYCh. 14 - Transcription factors that bind to DNA and...Ch. 14 - Prob. 4TYCh. 14 - For the lac operon, what would be the expected...Ch. 14 - Prob. 6TYCh. 14 - The trp operon is considered _____ blank operon...Ch. 14 - Prob. 8TYCh. 14 - Prob. 9TYCh. 14 - _____ blank refers to the process that allows a...Ch. 14 - Prob. 1CQCh. 14 - Transcriptional regulation often involves a...Ch. 14 - Prob. 3CQCh. 14 - Discuss the advantages and disadvantages of...Ch. 14 - Discuss the advantages and disadvantages of...
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- A nonsense mutation Select one: a. results in a larger protein being produced from the mutated gene b. will lead to premature termination of translation c. is the same as a silent mutation d. will lead to the premature termination of transcriptionarrow_forwardMutations in the promoter region of the β-globin gene indicate that some areas are more sensitive than others. When mutations occur in consensus sequences (modular elements such as GC box, CAAT box, TATA box), transcription usually A. increases b. stays about the same c. decreasesarrow_forwardLipid-soluble signaling molecules, such as testosterone, cross the membrane of all cells but only affect target cells because a. intracellular receptors are only present in target cells b. only target cells possess the cytosolic enzymes that transduce the testosterone c. target cells are the only cells that can initiate the phosphorylation cascade leading to the transcription factor d. only target cells retain the appropriate DNA segmentsarrow_forward
- Which of the following is true of ribosome rescue? (C & E wrong) A. The process produces a protein that is tagged for degradation. B. Proteases enter the A-site of the ribosome to degrade the C-terminus of the synthesized peptide. C. A partially translated mRNA becomes fully degraded before it can be translated further. D. No protein is produced in the process. E. Stalled ribosomes are released in the absence of a stop codon.arrow_forwardThe process of RNA interference may lead toa. the degradation of an mRNA.b. the inhibition of translation of an mRNA.c. the synthesis of an mRNA.d. both a and b.arrow_forwardWhich of the following gene expression regulatory mechanisms saves the most energy but takes the longest to fully express the genes once signaled? a. transcriptional regulation b. post-transcriptional regulation c. post-translational regulation d. translational regulationarrow_forward
- Which of these is used in the transcription of all genes? Choose all correct answers. A. Core promoter B. Proximal promoter C. Distal promoter D. General Transcription Factors E. Regulatory Transcription Factorsarrow_forwardArrange the statements in their proper order by writing the corresponding letter (e.g. A) for each statement in the space provided below. A. The single-stranded RNA would complement the target RNA. B. Gene expression is inactivated once the mRNA is no longer accessible for translation. C. The risk-induced silencing complex which is composed of RNA and protein subunits is formed. D. Double-stranded, non-coding RNA is cleaved by Dicer. E. The mRNA can be cleaved or remain bound by the RISC. 1. 2. 3. 4. 5.arrow_forwardA transcription factor (protein - orange/green) is bound to a promoter of a gene (DNA - blue) it regulates. What changes would result in the gene not being expressed? A. Mutations in the DNA sequence where the TF is bound B. Mutations in the DNA binding domain of the TF C. Mutations in the 3’UTR (untranslated region) of this gene A and B only B and C only A, B, and Carrow_forward
- The number of amino acids produced by translating the mRNA (3'AUGCUUAGUCGCGUA5') is : a. 4 b. 5 c. 1 d. 2 e. 3arrow_forwardThis molecule is most likely implicated in the renaturation of proteins. Select one: a. chaperone (HSP) b. kinase c. RISC d. proteasome e. transcriptional factorarrow_forwardHistone deacetylase (HDAC) enzymes a.Promote initiation of translation. b.Complex with hyperphosphorylated pRb. c.Repress E2F family activity. d.Add acetyl groups to E2F promoters. e.Promote initiation of transcription.arrow_forward
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