Biology: The Unity and Diversity of Life
15th Edition
ISBN: 9780357093795
Author: STARR
Publisher: CENGAGE LEARNING (CUSTOM)
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Chapter 14, Problem 4SQ
Summary Introduction
Introduction: Tay–Sachs disease is caused due to mutations in the HEXA gene that encodes lysosomal enzyme. It follows autosomal recessive inheritance, that is, two copies of mutated gene are required for the occurrence of the disease.
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If a mouse has a dominant phenotype (P_), how would you determine if it is
homozygous (PP) or heterozygous (Pp)?
Select one:
O a.
O b.
O c.
O d.
O e.
cross it to a mouse with the dominant trait but a similarly unknown genotype.
cross it to a mouse with the recessive trait.
cross it to a homozygous dominant mouse.
it cannot be determined.
cross it to a heterozygous dominant mouse.
O
Duchenne muscular dystrophy is sex linked and usuallyaffects only males. Victims of the disease become progressively weaker, starting early in life.a. What is the probability that a woman whose brotherhas Duchenne’s disease will have an affected child?b. If your mother’s brother (your uncle) had Duchenne’sdisease, what is the probability that you have receivedthe allele?c. If your father’s brother had the disease, what is theprobability that you have received the allele?
A woman with a rare autosomal recessive disorder was told that it was unlikely that her children would have the disorderas her husband did not have it. However, her first child has the disorder.
a. What is the most likely explanation?
b. Diagram the cross between the woman and her husband using a Punnett square, give the genotypic ratio (GR) and phenotypic ratio (PR) from the Punnett square.
c. Based on the Punnett square results, what is the chance that her next child will have the disorder?
Chapter 14 Solutions
Biology: The Unity and Diversity of Life
Ch. 14 - Prob. 1DAACh. 14 - Prob. 2DAACh. 14 - Prob. 3DAACh. 14 - Prob. 4DAACh. 14 - Prob. 5DAACh. 14 - Prob. 1SQCh. 14 - Pedigree analysis is necessary when studying human...Ch. 14 - A recognized set of symptoms that characterize a...Ch. 14 - Prob. 4SQCh. 14 - A trait that is present in a male child but not in...
Ch. 14 - Choose the statement that is incorrect. a. A son...Ch. 14 - Prob. 7SQCh. 14 - Prob. 8SQCh. 14 - Klinefelter syndrome (XXY) can most be easily...Ch. 14 - Prob. 10SQCh. 14 - Does the phenotype indicated by the red circles...Ch. 14 - G6PD deficiency is an X-Linked recessive disorder....Ch. 14 - Marian syndrome (Section 13.5) is inherited in an...Ch. 14 - Duchenne muscular dystrophy, which is inherited in...Ch. 14 - Human females have two X chromosomes (XX); males...Ch. 14 - A mutation on an autosome causes a particular...Ch. 14 - Expression of the SRY gene on the Y chromosome...Ch. 14 - The somatic cells of most individuals with Down...Ch. 14 - Mutations in the genes for clotting factor VIII...
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- Ichthyosis is a rare X-linked recessive disorder that is characterized by scaling of the skin around the neck and lower extremities. A young couple, Bart and Jenny, are expecting a child and are aware there might be a chance that their child could be affected by this disorder. Jenny (the wife) has ichthyosis, but Bart (her husband) is unaffected and completely normal with respect to the allele responsible for this disorder. A. Both Bart and Jenny were Biology majors as undergraduates. Knowing a little about the pattern of X-linked recessive inheritance, Bart and Jenny were concerned when ultrasound revealed that they would be having a son. However, genetic testing performed on the baby shortly after birth revealed that their newborn son, Mark, did not have ichthyosis. Explain how this could be the case, assuming that the gene responsible for ichthyosis is fully penetrant. If non-disjunction occurred, assume it happened in only one of the two parents, and during only one of the two…arrow_forwardA heterozygous individual is crossed with a homozygous recessive individual. a. Draw a Punnett square to represent this cross. b. What is the probability that an offspring will have a homozygous genotype? c. What is the probability that an offspring will have a dominant phenotype? d. What is the probability that three offspring will be produced that all carry the recessive allele but do not express the recessive phenotype?arrow_forwardIn man, muscular dystrophy is a condition in which the muscles waste away during early life and may result in a shorter life expectancy. It is due to a sex-linked, recessive gene. A certain couple has five children – three boys (ages 1yr, 3yrs, and 10yrs old) and two girls (ages 5yrs and 7yrs old). The oldest boy shows the symptoms of this disease. You are their family physician and they come to you for advice. What would you tell them about the chances of their other children developing the disease?arrow_forward
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