BIOCHEMISTRY (LOOSELEAF) >CUSTOM PKG<
8th Edition
ISBN: 9781305760738
Author: Campbell
Publisher: CENGAGE C
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Chapter 14, Problem 39RE
Interpretation Introduction
Interpretation:
The nature of
Concept introduction:
Cancer cells are the same as the normal cells of a human being; however, they are the modified mutant forms of the cells of the human body. The healthy cells get mutated by getting exposed to carcinogenic thins and harmful irradiations.
The anticancer agents kill both the normal cells and cancer cells, and the exploited part is that cancer cells are again formed at a faster rate than normal cells.
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The preferred substrate is T because the enzyme half-saturates at 7.00 mM for T, but requires 28.0 mM for U, and 112 mM for S.
b
Question Content Area
The rate constant k 2 with substrate S is 9.60×107 sec-1, with substrate T, k 2 = 6.00×104 sec-1, and with substrate U, k 2 = 2.40×106 sec-1.
Calculate the catalytic efficiency with S, T, and U.
Catalytic efficiency with S =
Catalytic efficiency with T =
Catalytic efficiency with U =
Does enzyme A use substrate S, substrate T, or substrate U with greater catalytic efficiency?
Fumerase catalyzes the conversion of fumerate to malate.
fumerate + H2O ⇋ malate
The turnover number, kcat, for fumerase is 8.00×102 sec-1. The Km of this enzyme for fumerate is 5.00×10-3 μmol mL-1.
a
In an experiment using 2.00×10-3 μmol·mL-1, what is Vmax?
Suppose you wanted to make a buffer of exactly pH 7.00 using KH2PO4 and Na2HPO4. If the final solution was 0.18 M in KH2PO4, you would need 0.25 M Na2HPO4. Now assume you wish to make a buffer at the same pH, using the same substances, but want the total phosphate molarity ([HPO42−]+[H2PO−4]) to equal 0.20 M. What concentration of the Na2HPO4 would be required?
Chapter 14 Solutions
BIOCHEMISTRY (LOOSELEAF) >CUSTOM PKG<
Ch. 14 - Prob. 1RECh. 14 - Prob. 2RECh. 14 - Prob. 3RECh. 14 - Prob. 4RECh. 14 - Prob. 5RECh. 14 - Prob. 6RECh. 14 - Prob. 7RECh. 14 - REFLECT AND APPLY Some viruses can undergo lysis...Ch. 14 - REFLECT AND APPLY What might be the...Ch. 14 - Prob. 10RE
Ch. 14 - Prob. 11RECh. 14 - Prob. 12RECh. 14 - Prob. 13RECh. 14 - Prob. 14RECh. 14 - Prob. 15RECh. 14 - Prob. 16RECh. 14 - Prob. 17RECh. 14 - Prob. 18RECh. 14 - Prob. 19RECh. 14 - RECALL What is innate immunity? What is acquired...Ch. 14 - RECALL What are the components of innate immunity?Ch. 14 - Prob. 22RECh. 14 - Prob. 23RECh. 14 - RECALL What is clonal selection?Ch. 14 - Prob. 25RECh. 14 - Prob. 26RECh. 14 - Prob. 27RECh. 14 - Prob. 28RECh. 14 - Prob. 29RECh. 14 - BIOCHEMICAL CONNECTIONS Explain the mode of action...Ch. 14 - Prob. 31RECh. 14 - Prob. 32RECh. 14 - Prob. 33RECh. 14 - Prob. 34RECh. 14 - Prob. 35RECh. 14 - REFLECT AND APPLY Why is it inaccurate to say,...Ch. 14 - REFLECT AND APPLY Describe the difference between...Ch. 14 - Prob. 38RECh. 14 - Prob. 39RECh. 14 - Prob. 40RECh. 14 - Prob. 41RECh. 14 - BIOCHEMICAL CONNECTIONS Describe the positive and...Ch. 14 - Prob. 43RECh. 14 - Prob. 44RECh. 14 - Prob. 45RECh. 14 - Prob. 46RECh. 14 - Prob. 47RECh. 14 - Prob. 48RECh. 14 - Prob. 49RECh. 14 - Prob. 50RECh. 14 - Prob. 51RECh. 14 - Prob. 52RECh. 14 - Prob. 53RECh. 14 - Prob. 54RE
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