BIOCHEMISTRY (LL)
9th Edition
ISBN: 9781337805100
Author: Campbell
Publisher: CENGAGE L
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Chapter 14, Problem 38RE
Interpretation Introduction
Interpretation:
The relationship between Ras, jun, and fos is to be explained.
Concept introduction:
Cancer is usually known as a disease of the DNA. Its roots lie in the change in the DNA of a cell. Due to these changes, the control of division can be lost. Two types of genes are affected by the mutation of DNA. These genes are tumor suppressor and oncogene.
The molecule due to which a cell becomes unable to grow and divide is known as a tumor suppressor.
The gene whose product encourages a cell for division and growth is known as an oncogene.
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Extracts from the bacterium Bacillus brevis contain a peptide with antibiotic properties. This peptide forms complexes with
metal ions and seems to disrupt ion transport across the cell membranes of other bacterial species, leading to bacterial death.
The structure of the peptide has been determined from a series of observations.
(a) Complete acid hydrolysis of the peptide, followed by amino acid analysis, yielded equimolar amounts of Leu, Orn, Phe, Pro,
and Val. Orn is ornithine, an amino acid not present in proteins but present in some peptides. Orn has the structure
H
'H,N-CH,
-
CH2 CH2 CH2 -
C - COO-
NH,
(b) The molecular weight of the peptide is approximately 1,200 Da.
(c) The peptide failed to undergo hydrolysis when treated with the enzyme carboxypeptidase. This enzyme catalyzes the
hydrolysis of the carboxyl-terminal residue of a polypeptide unless the residue is Pro or the peptide does not contain a free
carboxyl group.
(d) Treatment of the intact peptide with…
At a pH equal to the isoelectric point (pl) of alanine, the net charge of alanine is zero. Two structures can be drawn that have a
net charge of zero, but the predominant form of alanine at its pl is zwitterionic.
CH3
H,N
CH3
**
H¸N-C
H
Zwitterionic
H
Uncharged
OH
Select statements that explain why alanine is predominantly zwitterionic at its pl.
pk of alanine's amino group is more than its pl.
pk of alanine's carboxyl group is more than its pl.
PK of alanine's carboxyl group is less than its pl.
pk of alanine's amino group is less than its pl.
Correct Answer
What fraction of alanine is in the completely uncharged form at its pl?
1 in 2.2 × 107
1 in 1.6 × 10²
1 in 4680
1 in 9460
How does a voltage-gated sodium channel work? Specifically, how and why does a change in voltage trigger their opening? Please be detailed
Chapter 14 Solutions
BIOCHEMISTRY (LL)
Ch. 14 - Prob. 1RECh. 14 - Prob. 2RECh. 14 - Prob. 3RECh. 14 - Prob. 4RECh. 14 - Prob. 5RECh. 14 - Prob. 6RECh. 14 - Prob. 7RECh. 14 - REFLECT AND APPLY Some viruses can undergo lysis...Ch. 14 - REFLECT AND APPLY What might be the...Ch. 14 - Prob. 10RE
Ch. 14 - Prob. 11RECh. 14 - Prob. 12RECh. 14 - Prob. 13RECh. 14 - Prob. 14RECh. 14 - Prob. 15RECh. 14 - Prob. 16RECh. 14 - Prob. 17RECh. 14 - Prob. 18RECh. 14 - Prob. 19RECh. 14 - RECALL What is innate immunity? What is acquired...Ch. 14 - RECALL What are the components of innate immunity?Ch. 14 - Prob. 22RECh. 14 - Prob. 23RECh. 14 - RECALL What is clonal selection?Ch. 14 - Prob. 25RECh. 14 - Prob. 26RECh. 14 - Prob. 27RECh. 14 - Prob. 28RECh. 14 - Prob. 29RECh. 14 - BIOCHEMICAL CONNECTIONS Explain the mode of action...Ch. 14 - Prob. 31RECh. 14 - Prob. 32RECh. 14 - Prob. 33RECh. 14 - Prob. 34RECh. 14 - Prob. 35RECh. 14 - REFLECT AND APPLY Why is it inaccurate to say,...Ch. 14 - REFLECT AND APPLY Describe the difference between...Ch. 14 - Prob. 38RECh. 14 - Prob. 39RECh. 14 - Prob. 40RECh. 14 - Prob. 41RECh. 14 - BIOCHEMICAL CONNECTIONS Describe the positive and...Ch. 14 - Prob. 43RECh. 14 - Prob. 44RECh. 14 - Prob. 45RECh. 14 - Prob. 46RECh. 14 - Prob. 47RECh. 14 - Prob. 48RECh. 14 - Prob. 49RECh. 14 - Prob. 50RECh. 14 - Prob. 51RECh. 14 - Prob. 52RECh. 14 - Prob. 53RECh. 14 - Prob. 54RE
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