Developmental Biology
Developmental Biology
11th Edition
ISBN: 9781605354705
Author: Scott F. Gilbert, Michael J. F. Barresi
Publisher: Sinauer Associates is an imprint of Oxford University Press
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Chapter 14, Problem 2DQ
Summary Introduction

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The mechanism based on which cytokinesis occurs at the apical surface in the neuroepithelium. Whether the basal process maintained by the cells or not. Also explain the role of centrosomes in this nuclear migration.

Introduction:

The primary stem and progenitor cells of the vertebrate's central nervous system are known as neuroepithelium. These are the integral part of proliferating neural tube. During the process of neurogenesis radial glial progenitors and neuroepithelium display the characteristic apical-basal polarity. This polarity is accompanied by strict apical localization of specific proteins and cellular components like centrosomes, adherens junctions, apical protein kinase (APK) etc. The apical-basal polarity is essential for the symmetric and/or asymmetric distribution of cellular components during the cell cycle.

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