Concept explainers
(a)
Interpretation:
The function of Csk as tumor-suppressor gene or a proto-oncogene is to be determined.
Concept introduction:
Tumor suppressor genes that are responsible for regulating cell growth and division, repair DNA, and regulates apoptosis. Any mutation in the tumor suppressor gene can lead to uncontrolled cell division, ultimately resulting in cancer. Any normal gene upon mutation leading to a cause of cancer is termed as the proto-oncogene. The proto-oncogene upon permanent activation leads to cancer, while tumor suppressor gene upon inactivation causes cancer.
(b)
Interpretation:
The function of PTP1B as tumor-suppressor gene or a proto-oncogene is to be determined.
Concept introduction:
Tumor suppressor genes that are responsible for regulating cell growth and division, repair DNA, and regulates apoptosis. Any mutation in the tumor suppressor gene can lead to uncontrolled cell division, ultimately resulting in cancer. Any normal gene upon mutation leading to a cause of cancer is termed as the proto-oncogene. The proto-oncogene upon permanent activation leads to cancer, while tumor suppressor gene upon inactivation causes cancer.

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Chapter 14 Solutions
BIOCHEMISTRY (LOOSELEAF)-W/ACCESS
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- 2. Which one is the major organic product obtained from the following reaction sequence? HO A OH 1. NaOEt, EtOH 1. LiAlH4 EtO OEt 2. H3O+ 2. H3O+ OH B OH OH C -OH HO -OH OH D E .CO₂Etarrow_forwardwhat is a protein that contains a b-sheet and how does the secondary structure contributes to the overall function of the protein.arrow_forwarddraw and annotate a b-sheet and lable the hydrogen bonding. what is an example that contains the b-sheet and how the secondary structure contributes to the overall function of your example protein.arrow_forward
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