Microbiology with Diseases by Body System (5th Edition)
Microbiology with Diseases by Body System (5th Edition)
5th Edition
ISBN: 9780134477206
Author: Robert W. Bauman Ph.D.
Publisher: PEARSON
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Chapter 14, Problem 1CCS

A Deadly Carrier

Chapter 14, Problem 1CCS, A Deadly Carrier In 1937, a man employed to lay water pipes was found to be the source of a severe

In 1937, a man employed to lay water pipes was found to be the source of a severe epidemic of typhoid fever. The man, who had recovered from typhoid, was still an asymptomatic carrier of Salmonella enterica serotype Typhi, the bacterium that causes the disease. He habitually urinated at his job site and in the process contaminated the town’s water supply with bacteria from his bladder. Over 300 cases of typhoid fever developed, and 43 people died before the man was identified as the carrier.

  1. 1. How do you think health officials were able to identify the source of this typhoid epidemic?
  2. 2. Given that antibiotics were not generally available in 1937, how could health officials end the epidemic, short of removing the man from the job site?
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calculate the questions showing the solution including variables,unit and equations all the questiosn below using the data a) B1,   b) B2,   c) hybrid rate constant (1) d) hybrid rate constant (2) e) t1/2,dist f) t1/2,elim   g) k10 h) k12 i) k21 j) initial concentration (C0)   k) central compartment volume (V1) l) steady-state volume (Vss)   m) clearance (CL)  AUC (0→10 min) using trapezoidal rule n)  AUC (20→30 min) using trapezoidal rule o) AUCtail (AUC360→∞)   p) total AUC (using short cut method) q) volume from AUC (VAUC)

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Microbiology with Diseases by Body System (5th Edition)

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