FOUNDATIONS OF COLLEGE CHEM +KNEWTONALTA
FOUNDATIONS OF COLLEGE CHEM +KNEWTONALTA
15th Edition
ISBN: 9781119797807
Author: Hein
Publisher: WILEY
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Chapter 13.5, Problem 13.6P
Interpretation Introduction

Interpretation:

Among SO2, Br2 and CH3F molecules that are polar have to be determined.

Concept Introduction:

Molecules that have uneven electrons distributed among the bonded atoms are termed as polar molecules. In polar molecules, bonded atoms have difference in their electronegativity.

Dipole moment is the quantity that measures the polarity of the molecule. It is represented by an arrow. The arrow head point towards the more electronegative atom and its tail towards less electronegative atom. Polar molecules have some dipole moment or there dipole moment is canceled out. Whereas nonpolar molecule does not possess any dipole moment as there is no electronegative difference in it.

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Heparin is used as an anti-coagulant. A risk of heparin use is thrombocytopenia, or low platelet count. This risk is minimized with the use of low molecular weight heparins (LMWH), therefore it is desirable to separate LMWH from higher molecular weight heparins. The method of choice to do this is molecular exclusion chromatography. Below is a chromatogram from a molecular exclusion chromatographic run. Peaks ranging from A to J are clearly distinguishable. The heparin mixture that was analyzed had anywhere from 6 to 30 repeat units of monomer (where the heparin with 30 repeat units would be roughly five times the size of the heparin with six repeat units). a. Which letter most likely represents the peak with 6 repeat units given these heparin polymers were separated with molecular exclusion chromatography? b. Explain your reasoning describing the mechanism of retention in molecular exclusion chromatography. 100 80 60 60 Relative Abundance 40 40 E GH 20 20 B A 36 38 40 42 44 46 48 50 50…
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Chapter 13 Solutions

FOUNDATIONS OF COLLEGE CHEM +KNEWTONALTA

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