BIO 117/118-LAB MANUAL>CUSTOM<
15th Edition
ISBN: 9781307026757
Author: Mader
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Question
Chapter 13.4, Problem 1LO
Summary Introduction
To distinguish:
Active and passive immunity.
Introduction:
The third line defense is of two types, namely the active and passive immunity.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Chapter 13 Solutions
BIO 117/118-LAB MANUAL>CUSTOM<
Ch. 13.1 - Prob. 1LOCh. 13.1 - Prob. 2LOCh. 13.1 - Prob. 1CYPCh. 13.1 - Prob. 2CYPCh. 13.1 - Prob. 3CYPCh. 13.1 - Prob. 1ACh. 13.1 - Prob. 2ACh. 13.1 - Prob. 3ACh. 13.2 - Prob. 1LOCh. 13.2 - Prob. 2LO
Ch. 13.2 - Prob. 3LOCh. 13.2 - Prob. 4LOCh. 13.2 - Prob. 1CYPCh. 13.2 - Prob. 2CYPCh. 13.2 - Prob. 3CYPCh. 13.2 - Prob. 4CYPCh. 13.2 - Prob. 4ACh. 13.2 - Prob. 5ACh. 13.2 - Prob. 6ACh. 13.3 - Prob. 1LOCh. 13.3 - Prob. 2LOCh. 13.3 - Prob. 3LOCh. 13.3 - Prob. 4LOCh. 13.3 - Describe four mechanisms that result in the...Ch. 13.3 - Prob. 2CYPCh. 13.3 - Prob. 3CYPCh. 13.3 - Prob. 4CYPCh. 13.3 - Prob. 7ACh. 13.3 - Prob. 8ACh. 13.3 - Prob. 9ACh. 13.3 - Prob. 10ACh. 13.4 - Prob. 1LOCh. 13.4 - Prob. 2LOCh. 13.4 - Prob. 3LOCh. 13.4 - Prob. 1QTCCh. 13.4 - Prob. 2QTCCh. 13.4 - Prob. 3QTCCh. 13.4 - Prob. 1CYPCh. 13.4 - Prob. 2CYPCh. 13.4 - Prob. 3CYPCh. 13.4 - Prob. 4CYPCh. 13.4 - Prob. 11ACh. 13.4 - Prob. 12ACh. 13.5 - Prob. 1LOCh. 13.5 - Prob. 2LOCh. 13.5 - Prob. 3LOCh. 13.5 - Prob. 1QTCCh. 13.5 - Prob. 2QTCCh. 13.5 - Prob. 3QTCCh. 13.5 - Prob. 1CYPCh. 13.5 - Prob. 2CYPCh. 13.5 - Prob. 3CYPCh. 13.5 - Prob. 13ACh. 13.5 - Prob. 14ACh. 13.6 - Prob. 1LOCh. 13.6 - Prob. 2LOCh. 13.6 - Prob. 1QTCCh. 13.6 - Prob. 2QTCCh. 13.6 - Prob. 3QTCCh. 13.6 - Prob. 1CYPCh. 13.6 - Prob. 2CYPCh. 13.6 - Prob. 15ACh. 13.6 - Prob. 16ACh. 13 - Prob. S2.7BYBCh. 13 - Section 4.1 What are the roles of proteins in the...Ch. 13 - Prob. S11.5BYBCh. 13 - Why do you think that individuals born with XLA...Ch. 13 - Prob. 2CSCh. 13 - Some organisms, such as invertebrates, have no...Ch. 13 - Prob. 2TCCh. 13 - Prob. 3TC
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