GEN COMBO LOOSELEAF MICROBIOLOGY:A SYSTEMS APPROACH; CONNECT ACCESS CARD
5th Edition
ISBN: 9781260149364
Author: Marjorie Kelly Cowan Professor
Publisher: McGraw-Hill Education
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Chapter 13.3, Problem 21AYP
Summary Introduction
Toenlist:
The examples of emerging and reemerging infectious diseases
Concept introduction:
Emerging diseases are caused by microbes that have never been seen before. These diseases are caused by new microbes. Reemerging diseases are due to microorganisms that have become more prevalent in a population often due to increased virulence, travel, or due to lack of vaccination.
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Biopharmaceutics and Pharmacokinetics:Two-Compartment Model Instant Absorption Questions
SHOW ALL WORK, including equation used, variables used and each step to your solution, report your regression lines and axes names (with units if appropriate) :Calculate a-q
a) B1,
b) B2,
c) hybrid rate constant (1)
d) hybrid rate constant (2)
e) t1/2,dist
f) t1/2,elim
g) k10
h) k12
i) k21
j) initial concentration (C0)
k) central compartment volume (V1)
l) steady-state volume (Vss)
m) clearance (CL) AUC (0→10 min) using trapezoidal rule
n) AUC (20→30 min) using trapezoidal rule
o) AUCtail (AUC360→∞)
p) total AUC (using short cut method)
q) volume from AUC (VAUC)
Glitazones reduce insulin resistance by binding to a transcription factor in adipocytes, thereby reducing thesecretion of fatty acids. Glitazones are taken orally (in pill form). Using pharmacokinetic modeling, deriveequations to describe how the concentration of glitazones varies in the plasma as a function of time. Yourequations should be of the form: dCglitazone /dt = something, or dMglitazone /dt = something. Your model shouldinclude three compartments: the gut, the plasma, and the fatty tissues. Make sure to include a diagram thatillustrates your thinking, state all assumptions, and define your variables. Do not solve the equations.
Chapter 13 Solutions
GEN COMBO LOOSELEAF MICROBIOLOGY:A SYSTEMS APPROACH; CONNECT ACCESS CARD
Ch. 13.1 - Prob. 1AYPCh. 13.1 - Identify the sites where normal biota is found in...Ch. 13.1 - Discuss how the Human Microbiome Project has...Ch. 13.2 - Prob. 4AYPCh. 13.2 - Differentiate between a microbes pathogenicity and...Ch. 13.2 - List the steps a microbe has to take to get to the...Ch. 13.2 - Prob. 7AYPCh. 13.2 - Prob. 8AYPCh. 13.2 - Prob. 9AYPCh. 13.2 - Prob. 10AYP
Ch. 13.2 - Prob. 11AYPCh. 13.2 - Draw and label a curve representing the course of...Ch. 13.2 - Prob. 13AYPCh. 13.2 - List six different modes of horizontal...Ch. 13.2 - Define healthcare-associated infection, listing...Ch. 13.2 - List Kochs postulates, and explain alternative...Ch. 13.3 - Summarize the goals of epidemiology and the role...Ch. 13.3 - Identify why some diseases are notifiable, and...Ch. 13.3 - Prob. 19AYPCh. 13.3 - Discuss the three major types of epidemics, and...Ch. 13.3 - Prob. 21AYPCh. 13 - Prob. 1MCQCh. 13 - Prob. 2MCQCh. 13 - Prob. 3MCQCh. 13 - Prob. 4MCQCh. 13 - Prob. 5MCQCh. 13 - Prob. 6MCQCh. 13 - Prob. 7MCQCh. 13 - Prob. 8MCQCh. 13 - A positive antibody test for HIV would be a...Ch. 13 - Prob. 10MCQCh. 13 - Prob. 11TFCh. 13 - Prob. 12TFCh. 13 - Prob. 13TFCh. 13 - Prob. 14TFCh. 13 - Prob. 15TFCh. 13 - Based upon data from the Human Microbiome Project...Ch. 13 - Prob. 2CTQCh. 13 - Prob. 3CTQCh. 13 - Prob. 4CTQCh. 13 - Prob. 5CTQCh. 13 - Prob. 1VCCh. 13 - Appendix D provides guidance for working with...
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