EBK LIFE: THE SCIENCE OF BIOLOGY
11th Edition
ISBN: 8220103935432
Author: Sadava
Publisher: MAC HIGHER
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Chapter 13.1, Problem 4R
Summary Introduction
To review:
The experiments utilizing radioactive isotopes that would prove deoxyribonucleic acid (DNA) to be the genetic material and not proteins that are transferred to bacterial cells.
Introduction:
Some bacteria reproduce by various methods, one of them is by conjugation. During this type of reproduction, one of the bacteria carry an ‘F’ factor (genetic material called the plasmid), which is a determinant of donor cell, while the other bacteria does not carry any factor, this being the determinant of a recipient cell. The donor cell or the F+ bacteria, forms a conjugation tube between itself and the recipient cell (F−) in order to transfer the F-plasmid.
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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.
b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake?
Options:
A. Dose; Increase dose
B. Dose; Decrease dose
C. Dose; Do not change dose
D. Interval; Increase the interval between doses (give the drug less frequently)
E. Interval; Decrease the interval between doses (give the drug more frequently)
F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math
Chapter 13 Solutions
EBK LIFE: THE SCIENCE OF BIOLOGY
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genetic recombination strategies of bacteria CONJUGATION, TRANSDUCTION AND TRANSFORMATION; Author: Scientist Cindy;https://www.youtube.com/watch?v=_Va8FZJEl9A;License: Standard youtube license