Ch. 13-7 Mutations in the TYR gene may render its enzyme product—tyrosinase—nonfunctional.Individuals homozygous for such mutations cannot make the pigment melanin. Albinism, the absence of melanin, results. Humans and many other organisms can have this phenotype (right). Mutated tyrosinase alleles are recessive when paired with the normal allele in heterozygous individuals.In the following situations, what are the probable genotypes of the father, the mother, and their children?a. Both parents have normal phenotypes; some of their children have the albino phenotype and others are unaffected.b. Both parents and children have the albino phenotype.c. The mother and three children are unaffected; the father and one child have the albino phenotype.

Q: Ehler-Danlos syndrome is a rare disorder caused by a mutation ina gene that encodes a protein called…

A: Sir Gregor Mendel was a priest and a teacher who did the famous hybridization experiment on garden…

Q: Assume that a gene controls the expression of a trait in which affected children occur only in…

A: The question is asking about the mode of inheritance for a trait that appears to only affect…

Q: 77 10 9 The following 5 population genetics questions refer to this introduction: "Tay-Sachs disease…

A: # According to our guidelines we can answer only first 3 subparts. Upload other parts separately.…

Q: Phenylketonuria (PKU) is an autosomal recessive disease that results from a defect in an enzyme that…

A: With the chemical formula C 9H11NO2, phenylalanine (Phe or F) is an essential -amino acid. It can be…

Q: Bloom's Syndrome is an autosomal recessive disorder due to mutations in a helicase protein. Some of…

A: Bloom syndrome is an inherited disorder characterised by low height, a sun-induced skin rash, and a…

Q: Researchers have identified a gene in humans that (when mutated) causes tremors and unstable walking…

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: Members of a family are affected by a hereditary inflammatory and immunodeficiency disease. The…

A: Co-dominance:Co dominance is when the both genetypic alleles are seen in phenotype. Dominant…

Q: Ehler-Danlos syndrome is a rare disorder caused by a mutation ina gene that encodes a protein called…

A: The Ehler-Danlossyndrome is a disorder caused by a mutation in the gene codes for the protein…

Q: Leber congenital amaurosis (LCA) is a form  of congenital blindness in humans and is  known to be…

A: Leber congenital amaurosis (LCA) is a form of congenital blindness in humans and is known to be…

Q: Phenylketonuria (PKU) is an autosomal recessive disease that results from a defect in an enzyme that…

A: PKU or Phenylketonuria is a genetic disorder related to failed metabolism of an amino acid. The…

Q: catalyse the corresponding reactions indicated above. The recessive alleles a, b, c and d are…

A: Independent assortment is one type of genetic recombination. When chromosomes are sorted into…

Q: What is a heterochronic mutation? How does it affect the phenotypic outcome of an organism? What…

A: Mutation means sudden changes occur in DNA sequences. The mutation occurs randomly. It also occurs…

Q: Researchers have identified a gene in humans that (when mutant)causes severe dwarfism and mental…

A: Firstly, let's assume that we have isolated the normal gene from a healthy human, say gene X…

Q: Tay–Sachs disease is a severe autosomal recessive genetic disease that produces deafness, blindness,…

A: Tay-Sachs disease is a neurodegenerative disease that is caused by the mutation of the gene HEXA…

Q: define Silent mutations

A: point mutations result in inheritable changes that occur on a single random nucleotide on the DNA.…

Q: MSH2 is a gene commonly associated with HNPCC (Hereditary nonpolyposis colorectal cancer). This gene…

A: Hereditary nonpolyposis colorectal cancer (HNPCC), also known as Lynch syndrome, is an inherited…

Q: ckle-cell anemia is an interesting genetic disease. Normal homozygous individials (SS) have normal…

A:

Q: In retinoblastoma, a mutation in one allele of the RB1 tumorsuppressorgene can be inherited from the…

A: Retinoblastoma is a rare retinal disease that develops a malignant tumor in the retinal layers of…

Q: Brachyolmias are said to be heterogeneous and inherited in both dominant and recessive manners. What…

A: Brachyolmia is a rare type of bone disorder, which is genetically and clinically heterogenous in…

Q: Why Recessive CF disease alleles either produce no CFTR or produce nonfunctional or less functional…

A: Cystic fibrosis (CF) is a classical example of recessive disease. It is a disease that is inherited.

Q: (7) In a family-based alcohol use disorder genetic study, a total of 50 families, each with a pair…

A: We need to gauge hereditary inconsistancy because of heredity by utilizing the equation of…

Q: How many of the mutations listed below would lead to excessive cell growth when the cell was either…

A: Excessive growth occurs when a cell continuously divides and when there is no cell cycle arrest. Myc…

Q: The phenotype of a heterozygous mouse (Aa) is agouti.  The agouti banding pattern is due to altered…

A: * Homozygous dominant and Heterozygous will produce agouti that is AA or Aa respectively  and the…

Q: Explain the difference between a gain-of-functionmutation and a dominant-negative mutation. Why…

A: A mutation is referred to as a change in an organism's DNA sequence. Mutations can occur as a result…

Q: LO69 Identify whether a trait is epigenetic or genetic given an example. It has been shown that…

A: Epigenetic traits are heritable changes in gene expression and cellular phenotype caused by…

Q: Phenylketonuria (PKU) is caused by the absence of the enzyme phenylalanine hydroxylase, which…

A: Phenylketonuria (PKU) : Phenylketonuria (PKU) is an inherited metabolic disorder that affects the…

Q: Galactosemia is a metabolic condition, caused by a recessive allele, which prevents affected…

A: Galactosemia is a disorder of the metabolism of sugar that affects the body processes and metabolism…

Q: Match Genotype With Phenotype Consider a newly discovered organism that is bioluminescent.…

A: The genotype shows the genetic makeup of the individual in relation to the trait under study. It is…

Q: Sickle-cell anemia is a recessive autosomal disorderthat is caused by an amino acid substitution in…

A: The autosomal recessive disorder occurs as a result of the inheritance of two mutated genes that…

Q: Diamond–Blackfan anemia (DBA) is a rare, dominant genetic disorder characterized by bone marrow…

A: Dear student, as per our honor code we are allowed to answer one question at a time. since you have…

Q: Prader-Willi Syndrome (PWS) is caused by a mutation in an autosomal gene that is maternally…

A: Given information Prader-Willi Syndrome occurs by the mutated autosomal gene that is maternally…

Q: Why don’t all loss-of-function mutations that are recessive at the cellular level behave as…

A: Loss of function mutation refers to the mutation in a gene that leads to reduced or no function of…

Q: Is it possible for a severe mutation-causing hereditary condition to pass down from generation to…

A: A mutation can be defined as change in the sequence of genetic letters, called bases, within a…

Q: Bloom syndrome is an autosomal recessive disease that exhibitshaploinsufficiency. A recent survey…

A: A disease is a state of unhealthiness of the physical body, mind and social interaction. A disease…

Q: Explain Null (amorphic) and leaky mutations (hypomorphic), hypermorphic and neomorphic mutations

A: Mutations (changes in a gene sequence) can result in mutant alleles that no longer produce the same…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.