Ch. 13-7 Mutations in the TYR gene may render its enzyme product—tyrosinase—nonfunctional.Individuals homozygous for such mutations cannot make the pigment melanin. Albinism, the absence of melanin, results. Humans and many other organisms can have this phenotype (right). Mutated tyrosinase alleles are recessive when paired with the normal allele in heterozygous individuals.In the following situations, what are the probable genotypes of the father, the mother, and their children?a. Both parents have normal phenotypes; some of their children have the albino phenotype and others are unaffected.b. Both parents and children have the albino phenotype.c. The mother and three children are unaffected; the father and one child have the albino phenotype.

Human Anatomy & Physiology (11th Edition)
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Ch. 13-7

Mutations in the TYR gene may render its enzyme product—tyrosinase—nonfunctional.

Individuals homozygous for such mutations cannot make the pigment melanin. Albinism, the absence of melanin, results. Humans and many other organisms can have this phenotype (right). Mutated tyrosinase alleles are recessive when paired with the normal allele in heterozygous individuals.

In the following situations, what are the probable genotypes of the father, the mother, and their children?

a. Both parents have normal phenotypes; some of their children have the albino phenotype and others are unaffected.

b. Both parents and children have the albino phenotype.

c. The mother and three children are unaffected; the father and one child have the albino phenotype.

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