The heart is a pumping organ that pumps blood to different parts of the body by generating electrical impulses on its own. These electrical impulses generated in the heart are of major clinical significance and thus a system called electrocardiogram (ECG) is used to monitor the electrical activity of the heart. The ECG consists of waves, complexes, segments, and intervals that correspond to different activities of the heart such as the P wave, QRS complex, T wave, U wave, and QT interval. The ECG uses a characteristic graph paper having a square that denotes a particular time interval and this paper runs at the same speed as the ECG system.

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According to a recent study, 1 out of 50,000 people will be diagnosed with cystic fibrosis. Cystic fibrosis can be caused by a mutant form of the CFTR gene (dominant gene symbol is F and mutant is f). A. Using the rate of incidence above, what is the frequency of carriers of the cystic fibrosis allele for CFTR in the US? (3 pts) B. In a clinical study, 400 people from the population mentioned in (A.) were genotyped for BRCA1 Listed below are the results. Are these results in Hardy- Weinberg equilibrium? Use Chi Square to show whether or not they are. (3 pts) BRCA1 genotype # of women 390 BB Bb bb 10 0 12pt Paragraph L BIUAV V T² v V

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Chapter 13, Problem 7RQ

Summary Introduction

Introduction:

The heart is a pumping organ that pumps blood to different parts of the body by generating electrical impulses on its own. These electrical impulses generated in the heart are of major clinical significance and thus a system called electrocardiogram (ECG) is used to monitor the electrical activity of the heart. The ECG consists of waves, complexes, segments, and intervals that correspond to different activities of the heart such as the P wave, QRS complex, T wave, U wave, and QT interval. The ECG uses a characteristic graph paper having a square that denotes a particular time interval and this paper runs at the same speed as the ECG system.

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