The electrical activities of the heart are monitored by electrocardiogram that uses a system of leads, which are positive or negative electrodes. The leads are of two types, depending upon their activity, unipolar and bipolar. The unipolar leads monitor the activities of the heart between the positive electrode and the zero-electrical reference point at the center of the heart. The bipolar leads consist of two electrodes, one is positive and the other is negative. The standard unipolar leads are aVL, aVR, aVF, V1, V2, V3, V4, V5 and V6 while the bipolar leads are lead I, lead II and lead III.

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According to a recent study, 1 out of 50,000 people will be diagnosed with cystic fibrosis. Cystic fibrosis can be caused by a mutant form of the CFTR gene (dominant gene symbol is F and mutant is f). A. Using the rate of incidence above, what is the frequency of carriers of the cystic fibrosis allele for CFTR in the US? (3 pts) B. In a clinical study, 400 people from the population mentioned in (A.) were genotyped for BRCA1 Listed below are the results. Are these results in Hardy- Weinberg equilibrium? Use Chi Square to show whether or not they are. (3 pts) BRCA1 genotype # of women 390 BB Bb bb 10 0 12pt Paragraph L BIUAV V T² v V

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Chapter 13, Problem 2RQ

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The electrical activities of the heart are monitored by electrocardiogram that uses a system of leads, which are positive or negative electrodes. The leads are of two types, depending upon their activity, unipolar and bipolar. The unipolar leads monitor the activities of the heart between the positive electrode and the zero-electrical reference point at the center of the heart. The bipolar leads consist of two electrodes, one is positive and the other is negative. The standard unipolar leads are aVL, aVR, aVF, V1, V2, V3, V4, V5 and V6 while the bipolar leads are lead I, lead II and lead III.

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