The synthesis of alkyne 2 from epoxide 1 needs to be shown by taking 3-Bromo-1-propyne as a starting material. Concept Introduction: In the acid-catalyzed ring-opening of an epoxide with water, first proton transfer takes place and then nucleophilic attack takes place via the S N 2 mechanism. In the end, proton transfer step takes place that removes the charge formed after the attack of the neutral nucleophile on a more substituted position. Similarly, ring opening of epoxide can also take place in a basic medium. This results in an attack of the nucleophile on a less substituted position.

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Answer 1

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Chapter 13, Problem 72IP

Interpretation Introduction

Interpretation: The synthesis of alkyne 2 from epoxide 1 needs to be shown by taking 3-Bromo-1-propyne as a starting material.

Concept Introduction:

In the acid-catalyzed ring-opening of an epoxide with water, first proton transfer takes place and then nucleophilic attack takes place via the S_N2 mechanism. In the end, proton transfer step takes place that removes the charge formed after the attack of the neutral nucleophile on a more substituted position. Similarly, ring opening of epoxide can also take place in a basic medium. This results in an attack of the nucleophile on a less substituted position.

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Answer 2

Question

Chapter 13, Problem 72IP

Interpretation Introduction

Interpretation: The synthesis of alkyne 2 from epoxide 1 needs to be shown by taking 3-Bromo-1-propyne as a starting material.

Concept Introduction:

In the acid-catalyzed ring-opening of an epoxide with water, first proton transfer takes place and then nucleophilic attack takes place via the S_N2 mechanism. In the end, proton transfer step takes place that removes the charge formed after the attack of the neutral nucleophile on a more substituted position. Similarly, ring opening of epoxide can also take place in a basic medium. This results in an attack of the nucleophile on a less substituted position.

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Answer 3

Question

Chapter 13, Problem 72IP

Interpretation Introduction

Interpretation: The synthesis of alkyne 2 from epoxide 1 needs to be shown by taking 3-Bromo-1-propyne as a starting material.

Concept Introduction:

In the acid-catalyzed ring-opening of an epoxide with water, first proton transfer takes place and then nucleophilic attack takes place via the S_N2 mechanism. In the end, proton transfer step takes place that removes the charge formed after the attack of the neutral nucleophile on a more substituted position. Similarly, ring opening of epoxide can also take place in a basic medium. This results in an attack of the nucleophile on a less substituted position.

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Answer 4

Question

Chapter 13, Problem 72IP

Interpretation Introduction

Interpretation: The synthesis of alkyne 2 from epoxide 1 needs to be shown by taking 3-Bromo-1-propyne as a starting material.

Concept Introduction:

In the acid-catalyzed ring-opening of an epoxide with water, first proton transfer takes place and then nucleophilic attack takes place via the S_N2 mechanism. In the end, proton transfer step takes place that removes the charge formed after the attack of the neutral nucleophile on a more substituted position. Similarly, ring opening of epoxide can also take place in a basic medium. This results in an attack of the nucleophile on a less substituted position.

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Answer 5

Chapter 13, Problem 72IP

Interpretation Introduction

Interpretation: The synthesis of alkyne 2 from epoxide 1 needs to be shown by taking 3-Bromo-1-propyne as a starting material.

Concept Introduction:

In the acid-catalyzed ring-opening of an epoxide with water, first proton transfer takes place and then nucleophilic attack takes place via the S_N2 mechanism. In the end, proton transfer step takes place that removes the charge formed after the attack of the neutral nucleophile on a more substituted position. Similarly, ring opening of epoxide can also take place in a basic medium. This results in an attack of the nucleophile on a less substituted position.

Answer 6

Chapter 13, Problem 72IP

Interpretation Introduction

Interpretation: The synthesis of alkyne 2 from epoxide 1 needs to be shown by taking 3-Bromo-1-propyne as a starting material.

Concept Introduction:

In the acid-catalyzed ring-opening of an epoxide with water, first proton transfer takes place and then nucleophilic attack takes place via the S_N2 mechanism. In the end, proton transfer step takes place that removes the charge formed after the attack of the neutral nucleophile on a more substituted position. Similarly, ring opening of epoxide can also take place in a basic medium. This results in an attack of the nucleophile on a less substituted position.

Answer 7

Chapter 13, Problem 72IP

Interpretation Introduction

Interpretation: The synthesis of alkyne 2 from epoxide 1 needs to be shown by taking 3-Bromo-1-propyne as a starting material.

Concept Introduction:

In the acid-catalyzed ring-opening of an epoxide with water, first proton transfer takes place and then nucleophilic attack takes place via the S_N2 mechanism. In the end, proton transfer step takes place that removes the charge formed after the attack of the neutral nucleophile on a more substituted position. Similarly, ring opening of epoxide can also take place in a basic medium. This results in an attack of the nucleophile on a less substituted position.

Answer 8

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Answer 11

Ch. 13.2 - Prob. 1LTS Ch. 13.2 - Prob. 1PTS Ch. 13.2 - Prob. 2PTS Ch. 13.2 - Prob. 3ATS Ch. 13.4 - Prob. 4CC Ch. 13.5 - Prob. 2LTS Ch. 13.5 - Prob. 5PTS Ch. 13.5 - Prob. 6ATS Ch. 13.5 - Prob. 7CC Ch. 13.5 - Prob. 8CC

Solution Summary: The author explains that the synthesis of alkyne 2 from epoxide 1 needs to be shown by taking 3-Bromo-1-propyn as a starting material.

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