Biology
5th Edition
ISBN: 9781260487947
Author: BROOKER
Publisher: MCG
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Question
Chapter 13, Problem 6TY
Summary Introduction
Introduction: MicroRNAs (miRNAs) and small-interfering RNAs (siRNAs) mediate RNA interference through a complex called the RNA-induced Silencing Complex (RISC). RISC inhibits translation allowing regulation and providing genome defense against viruses through RNA interference.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
RNA interference is mediated by:
a. miRNA
b. tRNA
c. sgRNA
d. mRNA
In RNA silencing, siRNAs and miRNAs usually bind to which part of the mRNA molecules that they control?
a. 5′ UTR
b. Coding region
c. 3′ poly(A) tail
d. 3′ UTR
microRNAs (miRNAs) play important roles in gene regulation. What is the correct order of steps (using letters A - E) for miRNA biogenesis or formation?
A. Synthesis of pri-miRNA
B. Targeting of mRNA for translation repression or mRNA degradation
C. Loading into RISC complex
D. Formation of mature miRNA
E. Formation of pre-miRNA
O AECDB
O CDAEB
O ACBDE
O ADCEB
O ECABD
Chapter 13 Solutions
Biology
Ch. 13.1 - Prob. 1CCCh. 13.2 - Prob. 1CCCh. 13.3 - Prob. 1EQCh. 13.3 - Prob. 2EQCh. 13.3 - Prob. 3EQCh. 13.3 - Effects of Non-coding RNAs on Translation and mRNA...Ch. 13.4 - Non-coding RNAs and Protein Sorting Core Skill:...Ch. 13.5 - Core Skill: Modeling The goal of this modeling...Ch. 13 - Prob. 1TYCh. 13 - Prob. 2TY
Ch. 13 - Prob. 3TYCh. 13 - Prob. 4TYCh. 13 - Prob. 5TYCh. 13 - Prob. 6TYCh. 13 - With regard to miRNAs and siRNAs, which of the...Ch. 13 - Cas1 and Cas2 proteins play a role during which of...Ch. 13 - Which of the following components bind to...Ch. 13 - Abnormalities in the expression of ncRNAs are...Ch. 13 - An ncRNA may have one or more of the following...Ch. 13 - What is RNA interference (RNAi)? Explain how the...Ch. 13 - Prob. 3CQCh. 13 - Prob. 1COQCh. 13 - Go to the PubMed website and search for non-coding...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Following is the sequence of a segment of mRNA: CGA AAA GUU UUU What are the anticodons of the tRNAs that will be used for translating this mRNA segment? Group of answer choices a. CGA, AAA, GUU, and UUU b. ARG, LYS, VAL, and PHE c. GCU, UUU, CAA, and AAA d. Arg-Lys-Val-Phe e. GCT, TTT, CAA, and AAAarrow_forwardWhat is the predicted size of the corresponding mature mRNA in base pairs (bp), excluding the 5’ cap and 3’ poly- A tail? a. 220bp b. 295bp c. 140bp d. 435bparrow_forwardGive typing answer with explanation and conclusionarrow_forward
- What is the mechanism by which an RNA transcript can be used to silence expression of the same gene? a. What is the name of this mechanism? b. Briefly describe the steps of the process and the two possible fates for the silenced RNA transcript? c. Predict how a transversion in the miRNA sequence would affect this process.arrow_forwardWhich translation factor mediates the aminoacyl-tRNA entry into the A site of the ribosome? A. EF-Tu B. EF-Ts C. EF-G D. IF1arrow_forwardMatch each factor involved in miRNA biogenesis with its function pri-miRNA forms a hairpin that is recognized by Drosha and DGCR8 A. Drosha and DGCR8 cleave non-complementary tails off pri-miRNAS B. exportin 5 C. transfers pre-miRNA from the nucleus to the cytoplasm Dicer D. processes pre-miRNAS into mature 20-25 nt miRNAS binds to mRNAs and represses their translation or targets them for degradation Е. RISCarrow_forward
- Arrange the statements in their proper order by writing the corresponding letter (e.g. A) for each statement in the space provided below. A. The single-stranded RNA would complement the target RNA. B. Gene expression is inactivated once the mRNA is no longer accessible for translation. C. The risk-induced silencing complex which is composed of RNA and protein subunits is formed. D. Double-stranded, non-coding RNA is cleaved by Dicer. E. The mRNA can be cleaved or remain bound by the RISC. 1. 2. 3. 4. 5.arrow_forwardWhich part of a tRNA molecule acts as an amino acid attachment site? a. the 5' end b. the 3' end c. the anticodon d. any of thesearrow_forwardWhich of the following is NOT true of miRNAs? A. Pri-miRNAs are processed by Drosha in the nucleus to form pre-miRNAs which are cleaved by dicer in the cytoplasm to generate a miRNA. B. miRNAs always lead to the degradation of their mRNA targets. C. miRNAs can be encoded within the vertebrate genome within introns and within intergenic regions. D. miRNAs can generally target more than one mRNAarrow_forward
- Which eukaryotic RNA polymerase (RNA pol I,pol II, or pol III) transcribes which genes?a. tRNAsb. mRNAsc. rRNAsd. miRNAsarrow_forwardWhy might a single base-pair mutation in eukaryotic mRNA be less serious than one in prokaryotic mRNA? a. If the mutation occurs in the 5' end of the start site, it will not affect the gene product. b. If the mutation occurs in the exon, it will not affect the gene product. c. If the mutation occurs in the splice site of a transcript with alternative splicing, only one gene product may affected. O d. If the mutation occurs in the intron or not in the splice site of a transcript with alternative splicing, it will nc affect the gene product. O e. If the mutation occurs in the 3' end of the start site, it will not affect the gene product. OLIE STIC N 1Aarrow_forwardWhat is the name of the process that adds a modified guanosine nucleotide to the 5’ phosphates of pre-mRNAs in eukaryotes? a. splicing b. polyadenylation c. capping d. nuclear export e. photophosphorylationarrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSON
Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
Anatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
QCE Biology: Introduction to Gene Expression; Author: Atomi;https://www.youtube.com/watch?v=a7hydUtCIJk;License: Standard YouTube License, CC-BY