Concept explainers
Introduction: Molecules that are formed from the transcription of DNAs but do not get translated to proteins are called non-coding RNAs (ncRNAs). nRNAs affect gene expression. Examples of ncRNAs that are involved in epigenetics are miRNAs, piRNAs and siRNAs.
Answer to Problem 1TY
Correct answer: DNA and RNA both bind to an ncRNA through base pairing. Hence, the correct answer is option e.
Explanation of Solution
Reason for correct answer:
Many different functions are carried out by ncRNAs because they have the ability to bind with many different types of molecules, such as DNA, other mRNAs, proteins or other small molecules. ncRNAs can affect different processes, such as
Option e. is given as “both a and b”.
The types of molecules that could bind to an ncRNA through base pairing are DNA and RNA. Hence, the correct answer is option e.
Reasons for incorrect answer:
Option a. is given as, “DNA”.
ncRNAs affect gene expression by binding to different molecules, such as DNA, mRNA, proteins, and small molecules. They play a very important role in affecting transcriptional, post-transcriptional, and epigenetic regulation. On binding to DNA molecules, ncRNAs may affect DNA replication, transcription, and translation. This is possible through complementary base pairing of ncRNAs with DNA strands. However, ncRNAs bind to both RNAs and DNAs. Hence, option a. is incorrect.
Option b. is given as, “RNA”.
By binding to different molecules, such as DNA, mRNA, proteins, and small molecules, ncRNAs affect gene expression. Transcriptional, post-transcriptional and epigenetic regulation occurs as a result of this binding. Binding of ncRNAs to other mRNAs is possible through complementary base pairing. However, ncRNAs bind to both DNAs and RNAs. Hence, option b. is incorrect.
Option c. is given as, “protein”.
ncRNAs bind to different molecules such as DNA, mRNA, proteins and small molecules. They play a very important role in affecting transcriptional, post-transcriptional, and epigenetic regulation. Binding of ncRNAs with proteins does not occur by the process of complementary base pairing as proteins do not have bases. Hence, option c. is incorrect.
Option d. is given as, “small molecule”.
Small molecules bind to ncRNAs and help in maintaining transcriptional, post-transcriptional, and epigenetic regulation. Binding of ncRNAs with small molecules does not occur by the process of complementary base pairing as small molecules do not have bases. Hence, option d. is incorrect.
Hence, the options a., b., c., and d. are incorrect.
Thus, DNA and RNA both bind to ncRNA through base pairing to carry out regulation of transcription, translation, and epigenetic modifications.
Want to see more full solutions like this?
Chapter 13 Solutions
Biology
- Which of the following is an intron and intergenic coded long transcripts, processed into stem and loop structures that may bind specifically or otherwise? a. spliceosome RNA b. LncRNA c. miRNA d. piRNA e. siRNAarrow_forwardDefine the following terms: a. peptidyl transferase center b. GTPase associated region c. 70S bacterial ribosome d. decoding center e. Shine–Dalgarno sequencearrow_forwardConsider this sequence below: GAG TAC ACG AGT GGA Which of the following options is an example of a non-synonymous point mutation? (remember to translate to mRNA!) A. GAG TAC AAT CGA GTG GA B. GAG TAC ACG GGT GGA C. GAG TAC A–G AGT GGA D. GAG TAC ACG AGA GGAarrow_forward
- Which of the following makes alternative RNA splicing possible? Group of answer choices A. Parts of a gene can function as exons or introns B. DNA methylation C. Parts of a gene can be either transcribed or not D. Histone Acetylation E. Parts of a gene can bind to RNA polymerase or notarrow_forwardExplain how each of the following processes complicates the concept of colinearity. a. Trans-splicing b. Alternative splicing c. RNA editingarrow_forwardDefine the following terms: a. open reading frame b. degenerate coding system c. nonoverlapping coding sequence d. codon e. anticodonarrow_forward
- Which of the following are involved in posttranscriptional control? a. control of RNA splicing b. control of RNA shuttling c. control of RNA stability d. all of the abovearrow_forwardWhen an ncRNA functions as a decoy, ita. contains binding sites for many different proteins, therebypromoting the formation of a large complex.b. recognizes other ncRNAs and sequesters them, therebypreventing them from working.c. can alter its conformation, allowing it to switch betweenactive and inactivate conformations.d. may physically prevent or block a cellular process fromhappening.arrow_forwardResearchers screening the blood of an advanced prostate cancer patient identified a 21 base pair long RNA molecule deemed to be potential importance as a biomarker of disease. Subsequent experiments using this molecule showed that it decreased retinoblastoma (Rb) protein levels. Based on this activity, what type of RNA is this molecule? A. Transfer RNA B. Micro RNA C. Circular RNA D. Ribosomal RNA E. Messenger RNAarrow_forward
- Which of the following amino acids is carried by the tRNA that initiates translation in eukaryotes? a.Tryptophan b.Leucine c.Methionine d.Alaninearrow_forwardWhich of the following is not a possible size (in bp) of the mature mRNA? a. 205bp b. 180bp c. 150bp d. 100bparrow_forwardThe mature m-RNA is capped by which of the following heterocyclic bases (or which of the following heterocyclic bases are present on the cap of a mature m-RNA? a. 5-methylcytosine b. 5-methyguanine c. 7-methylguanine d. 7-methylcytosinearrow_forward
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education