a) Summarize the Watson & Crick model of DNA as they put forth in their letter to Nature.  b) Draw a picture of Watson and Crick's proposed DNA structure, and include measurements they indicate.  c) Is the model they gave still considered accurate?

a) Give a definition of STRs. b) Must each copy of a chromosome have the same number of repeats? c) How many STRs does the FBI use for identification in a criminal case?

What part of the replication process is depicted in the photo you uploaded below? DNA polymerase I and ligase in action:

What is the purpose of each of the following steps of the DNA isolation process?  Blending Salt Detergent  Meat tenderizer  Ice-cold isopropanol

Using the envelope depiction we presented in class, draw out chemical structures for thefollowing oligonucleotides. You can abbreviate the bases as Ade, Cyt, Gua, Thy, Ura. A. d(GACA)B. p(d(TATA))C. GUCUp

TerpenesA. Provide a reasonable mechanism for the production of geranyl pyrophosphate from IPP andDMAPPB. How many molecules of IPP and how many molecules of DMAPP would you need to makefarnesyl pyrophosphate

Draw the enol form of Thymine, and show how this tautomer could form a Watson-Crickbase pair with Guanine. If this happened, what would be the consequence?

Consider the two isoprenoid precursors IPP and DMAPP.A. Which one is more susceptible to SN1 reaction? Explain your answerB. Which is a more likely nucleophile? Explain your answer

Draw the structure of the anti-HIV drug AZT (zidovudine), which stops retro-viral DNAsynthesis. When AZT is taken up by cells, it is converted to AZT triphosphate. Explain how thiscompound could interfere with DNA synthesis