(A) To write: Why an inherited deficiency in complement components C3 or C4 can result in less efficient clearance of immune complexes from blood and lymph than normal. Introduction: The C3 component of the complement system is an opsonin that promotes the activity of phagocytes. It helps in the formation of pus (pyogenic effect). The C4 is a glycoprotein involved in inflammatory responses and is called an anaphylatoxin. Their deficiencies cause some major immune diseases.

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Answer 1

Question

Chapter 13, Problem 4Q

Summary Introduction

(A)

To write:

Why an inherited deficiency in complement components C3 or C4 can result in less efficient clearance of immune complexes from blood and lymph than normal.

Introduction:

The C3 component of the complement system is an opsonin that promotes the activity of phagocytes. It helps in the formation of pus (pyogenic effect). The C4 is a glycoprotein involved in inflammatory responses and is called an anaphylatoxin. Their deficiencies cause some major immune diseases.

Summary Introduction

(B)

To write:

To highlight what clinical symptoms the above can lead to.

Introduction:

In general, the inherited deficiency of complement components lead to accumulation of immune complexes in the body. They include systemic lupus erythematosus, vasculitis, glomerulonephritis and others.

Summary Introduction

(C)

To write:

To mention and explain the only known effect of deficiencies in complement components C5-C9

Introduction:

The deficiencies of C5-C9 complement components makes one predisposed to infection by Neisseria.

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Question #3: In the KeyGene paper, the authors state that it would be useful if pollen from an apomict would transmit apomixis-inducing genes to the female in the cross (assuming the pollen is viable). Assuming there was just one gene conferring gametophytic obligate apomixis, and that the two parents are inbreds, what would be the consequences of such a cross if: a) The apomixis was a dominant trait? Indicate the genotypes and phenotypes (apomict or non- apomict) of the parents, F1 and F2 generations. Remember to include the expected genotypic and phenotypic ratios (or percentages) in the F1 and F2 generations, and to position the female first (left side) in the parental cross. b) The apomixis was a recessive trait? Indicate the genotypes and phenotypes (apomict or non- apomict) of the parents, F1 and F2 generations. Remember to include the expected genotypic and phenotypic ratios (or percentages) in the F1 and F2 generations, and to position the female first (left side) in the…

Question #5: Assume that two genes are identified that confer gametophytic facultative apomixis in soybean. The genes show independent assortment. Recessive alleles at both loci are required for the facultative apomixis. Facultative apomixis is triggered when the temperature at pollination is above 20 degrees C. At temperatures below 20 degrees C, all reproduction is sexual, independent of genotype. A facultative apomict male, capable of producing viable pollen, was crossed with a sexually reproducing female. Assuming the parents are completely inbred, what are the predicted phenotypic ratios (apomict: non-apomict) for the F1, F2, and DH (F1-derived) generations at each of the following temperatures*: a) 15°C? b) 25°C? *for full credit, show crosses and genotypes where appropriate. Remember to position the female first (left side) in the cross. Type your answer here:

Answer 2

Question

Chapter 13, Problem 4Q

Summary Introduction

(A)

To write:

Why an inherited deficiency in complement components C3 or C4 can result in less efficient clearance of immune complexes from blood and lymph than normal.

Introduction:

The C3 component of the complement system is an opsonin that promotes the activity of phagocytes. It helps in the formation of pus (pyogenic effect). The C4 is a glycoprotein involved in inflammatory responses and is called an anaphylatoxin. Their deficiencies cause some major immune diseases.

Summary Introduction

(B)

To write:

To highlight what clinical symptoms the above can lead to.

Introduction:

In general, the inherited deficiency of complement components lead to accumulation of immune complexes in the body. They include systemic lupus erythematosus, vasculitis, glomerulonephritis and others.

Summary Introduction

(C)

To write:

To mention and explain the only known effect of deficiencies in complement components C5-C9

Introduction:

The deficiencies of C5-C9 complement components makes one predisposed to infection by Neisseria.

Expert Solution & Answer

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Answer 3

Question

Chapter 13, Problem 4Q

Summary Introduction

(A)

To write:

Why an inherited deficiency in complement components C3 or C4 can result in less efficient clearance of immune complexes from blood and lymph than normal.

Introduction:

The C3 component of the complement system is an opsonin that promotes the activity of phagocytes. It helps in the formation of pus (pyogenic effect). The C4 is a glycoprotein involved in inflammatory responses and is called an anaphylatoxin. Their deficiencies cause some major immune diseases.

Summary Introduction

(B)

To write:

To highlight what clinical symptoms the above can lead to.

Introduction:

In general, the inherited deficiency of complement components lead to accumulation of immune complexes in the body. They include systemic lupus erythematosus, vasculitis, glomerulonephritis and others.

Summary Introduction

(C)

To write:

To mention and explain the only known effect of deficiencies in complement components C5-C9

Introduction:

The deficiencies of C5-C9 complement components makes one predisposed to infection by Neisseria.

Expert Solution & Answer

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Answer 4

Question

Chapter 13, Problem 4Q

Summary Introduction

(A)

To write:

Why an inherited deficiency in complement components C3 or C4 can result in less efficient clearance of immune complexes from blood and lymph than normal.

Introduction:

The C3 component of the complement system is an opsonin that promotes the activity of phagocytes. It helps in the formation of pus (pyogenic effect). The C4 is a glycoprotein involved in inflammatory responses and is called an anaphylatoxin. Their deficiencies cause some major immune diseases.

Summary Introduction

(B)

To write:

To highlight what clinical symptoms the above can lead to.

Introduction:

In general, the inherited deficiency of complement components lead to accumulation of immune complexes in the body. They include systemic lupus erythematosus, vasculitis, glomerulonephritis and others.

Summary Introduction

(C)

To write:

To mention and explain the only known effect of deficiencies in complement components C5-C9

Introduction:

The deficiencies of C5-C9 complement components makes one predisposed to infection by Neisseria.

Expert Solution & Answer

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Answer 5

Chapter 13, Problem 4Q

Summary Introduction

(A)

To write:

Why an inherited deficiency in complement components C3 or C4 can result in less efficient clearance of immune complexes from blood and lymph than normal.

Introduction:

The C3 component of the complement system is an opsonin that promotes the activity of phagocytes. It helps in the formation of pus (pyogenic effect). The C4 is a glycoprotein involved in inflammatory responses and is called an anaphylatoxin. Their deficiencies cause some major immune diseases.

Summary Introduction

(B)

To write:

To highlight what clinical symptoms the above can lead to.

Introduction:

In general, the inherited deficiency of complement components lead to accumulation of immune complexes in the body. They include systemic lupus erythematosus, vasculitis, glomerulonephritis and others.

Summary Introduction

(C)

To write:

To mention and explain the only known effect of deficiencies in complement components C5-C9

Introduction:

The deficiencies of C5-C9 complement components makes one predisposed to infection by Neisseria.

Answer 6

Chapter 13, Problem 4Q

Summary Introduction

(A)

To write:

Why an inherited deficiency in complement components C3 or C4 can result in less efficient clearance of immune complexes from blood and lymph than normal.

Introduction:

The C3 component of the complement system is an opsonin that promotes the activity of phagocytes. It helps in the formation of pus (pyogenic effect). The C4 is a glycoprotein involved in inflammatory responses and is called an anaphylatoxin. Their deficiencies cause some major immune diseases.

Answer 7

Chapter 13, Problem 4Q

Summary Introduction

(A)

To write:

Why an inherited deficiency in complement components C3 or C4 can result in less efficient clearance of immune complexes from blood and lymph than normal.

Introduction:

The C3 component of the complement system is an opsonin that promotes the activity of phagocytes. It helps in the formation of pus (pyogenic effect). The C4 is a glycoprotein involved in inflammatory responses and is called an anaphylatoxin. Their deficiencies cause some major immune diseases.

Answer 8

Summary Introduction

(B)

To write:

To highlight what clinical symptoms the above can lead to.

Introduction:

In general, the inherited deficiency of complement components lead to accumulation of immune complexes in the body. They include systemic lupus erythematosus, vasculitis, glomerulonephritis and others.

Answer 9

Summary Introduction

(B)

To write:

To highlight what clinical symptoms the above can lead to.

Introduction:

In general, the inherited deficiency of complement components lead to accumulation of immune complexes in the body. They include systemic lupus erythematosus, vasculitis, glomerulonephritis and others.

Answer 10

Summary Introduction

(C)

To write:

To mention and explain the only known effect of deficiencies in complement components C5-C9

Introduction:

The deficiencies of C5-C9 complement components makes one predisposed to infection by Neisseria.

Answer 11

Summary Introduction

(C)

To write:

To mention and explain the only known effect of deficiencies in complement components C5-C9

Introduction:

The deficiencies of C5-C9 complement components makes one predisposed to infection by Neisseria.

Answer 12

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Answer 13

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Answer 14

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Answer 15

Ch. 13 - Prob. 1Q Ch. 13 - Prob. 2Q Ch. 13 - Prob. 3Q Ch. 13 - Prob. 4Q Ch. 13 - Prob. 5Q Ch. 13 - Prob. 6Q Ch. 13 - Prob. 7Q Ch. 13 - Prob. 8Q Ch. 13 - Prob. 9Q Ch. 13 - Prob. 10Q

(B) To write: To highlight what clinical symptoms the above can lead to. Introduction: In general, the inherited deficiency of complement components lead to accumulation of immune complexes in the body. They include systemic lupus erythematosus, vasculitis, glomerulonephritis and others.

(C) To write: To mention and explain the only known effect of deficiencies in complement components C5-C9 Introduction: The deficiencies of C5-C9 complement components makes one predisposed to infection by Neisseria.

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Chapter 13 Solutions

(B)

To write:

To highlight what clinical symptoms the above can lead to.

Introduction:

In general, the inherited deficiency of complement components lead to accumulation of immune complexes in the body. They include systemic lupus erythematosus, vasculitis, glomerulonephritis and others.

(C)

To write:

To mention and explain the only known effect of deficiencies in complement components C5-C9

Introduction:

The deficiencies of C5-C9 complement components makes one predisposed to infection by Neisseria.