
Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
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Textbook Question
Chapter 13, Problem 4P
Answers to all problems are at the end of this book. Detailed solutions are available in the Student Solutions Manual, Study Guide, and Problems Book.
Graphing the Results from Kinetics Experiments with Enzyme Inhibitors The following kinetic data were obtained for an enzyme in the absence of any inhibitor (1), and in the presence of two different inhibitors (2) and (3) at 5 mM concentration. Assume [ET] is the same in each experiment.
Graph these data as Lineweaver-Burk plots and use your graph to find answers to a. and b.
a. Determine Vmax and Km for the enzyme.
b. Determine the type of inhibition and the K1 for each inhibitor.
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1. What is the isoelectric point of glutamic acid?
(Glutamic acid has pKa1 2.10, pKa2 4.07, pKaз 9.47)
A) pH 2.1
D) pH 6.8
B) pH 3.1
C) pH 4.1
E) pH 9.5
HO
NH2
Glutamic acid
(shown without charges)
OH
Br
Mg, ether
1. HCHO
(formaldehyde)
2. H+, H₂O
PCC
1. NH3, HCN
?
(pyridinium chlorochromate)
2. H2O, HCI
11. Which one of the following compounds is the major organic product of the
series of reactions shown above?
Ph.
Ph.
OH
NH2₂
A
Ph.
Ή
NH2
B
OH
Ph
Η
Ph
OH
NH2
NH2₂
NH₂
C
D
E
B
A
6. Which ONE of the
labeled bonds in the
tripeptide on the right
is a peptide bond:
H₂N
N
'N'
OH
C
H
A, B, C, D or E?
HN
E
OH
Chapter 13 Solutions
Biochemistry
Ch. 13 - Answers to all problems are at the end of this...Ch. 13 - Answers to all problems are at the end of this...Ch. 13 - Answers to all problems are at the end of this...Ch. 13 - Answers to all problems are at the end of this...Ch. 13 - Answers to all problems are at the end of this...Ch. 13 - Answers to all problems are at the end of this...Ch. 13 - Answers to all problems are at the end of this...Ch. 13 - Answers to all problems are at the end of this...Ch. 13 - Answers to all problems are at the end of this...Ch. 13 - Answers to all problems are at the end of this...
Ch. 13 - Answers to all problems are at the end of this...Ch. 13 - Answers to all problems are at the end of this...Ch. 13 - Answers to all problems are at the end of this...Ch. 13 - Answers to all problems are at the end of this...Ch. 13 - Prob. 15PCh. 13 - Prob. 16PCh. 13 - Prob. 17PCh. 13 - Prob. 18PCh. 13 - Answers to all problems are at the end of this...
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