Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
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Chapter 13, Problem 14P
Answers to all problems are at the end of this book. Detailed solutions are available in the Student Solutions Manual, Study Guide, and Problems Book.
Quantitative Relationships Between Rate Constants to Calculate Km, Kinetic Efficiency (kcat/Km) and Vmax - VI The enzyme catalase catalyzes the decomposition of hydrogen peroxide:
a. In an experiment using 3 nanomole/L of catalase, what is Vmax?
b. What is v when [H2O2] = 0.75 M?
c. What is the catalytic efficiency of catalase?
d. Does catalase approach "catalytic perfection"?
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Deficiencies of carnitine, carnitine acyltransferases, or carnitine/acylcarnitine translocase affect the metabolism of long-chain
fatty acids. Many of the symptoms are similar, and include hypoketotic hypoglycemia, low ketone levels and low blood sugar
with fasting, and damage to the liver, heart, or muscles due to fatty acid buildup in those tissues. Symptom severity varies with
the form of the deficiency.
The following abbreviations are used: carnitine acyltransferase (carnitine palmitoyltransferase), CPT and carnitine/acylcarnitine
translocase, CACT.
Identify each symptom or effect as a deficiency of CPT I, CPT II, or CACT.
CPT I deficiency
CPT II deficiency
CACT deficiency
Answer Bank
acyl carnitine not transported into mitochondrial matrix
acyl carnitine not converted to carnitine in matrix
long-chain fatty acids not transferred to carnitine
Diabetes is a group of metabolic diseases characterized by abnormal regulation of blood glucose levels. If left untreated,
diabetes leads to chronic hyperglycemia and numerous pathological complications.
Classify each characteristic according to whether it best describes type 1 or type 2 diabetes mellitus.
Type 1 diabetes
Answer Bank
Type 2 diabetes
linked with obesity and insufficient exercise
characterized by insulin deficiency
typically develops in adulthood
characterized by insulin unresponsiveness
typically develops during childhood
an autoimmune disease
Draw the structure of the dipeptide
Gly-lle at physiological
pH
Chapter 13 Solutions
Biochemistry
Ch. 13 - Answers to all problems are at the end of this...Ch. 13 - Answers to all problems are at the end of this...Ch. 13 - Answers to all problems are at the end of this...Ch. 13 - Answers to all problems are at the end of this...Ch. 13 - Answers to all problems are at the end of this...Ch. 13 - Answers to all problems are at the end of this...Ch. 13 - Answers to all problems are at the end of this...Ch. 13 - Answers to all problems are at the end of this...Ch. 13 - Answers to all problems are at the end of this...Ch. 13 - Answers to all problems are at the end of this...
Ch. 13 - Answers to all problems are at the end of this...Ch. 13 - Answers to all problems are at the end of this...Ch. 13 - Answers to all problems are at the end of this...Ch. 13 - Answers to all problems are at the end of this...Ch. 13 - Prob. 15PCh. 13 - Prob. 16PCh. 13 - Prob. 17PCh. 13 - Prob. 18PCh. 13 - Answers to all problems are at the end of this...
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