The probability that one of the surviving kittens with parents having the allele M L M associated with taillessness in Manx cats will be heterozygous. Concept introduction: The mutated M L allele is associated with taillessness in Manx cats. The homozygous M L M L allele is called as lethal alleles, as they cause death of the kitten as embryo itself due to defects of the spinal cord. Lethal alleles are those in heterozygous or homozygous form that causes death of the individual during embryonic development itself. The probability reduces in such cases, as those alleles will not be transferred to the next generation as the allele is lost with the death of the embryo.

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Chapter 13, Problem 4GP

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To explain: The probability that one of the surviving kittens with parents having the allele M^LM associated with taillessness in Manx cats will be heterozygous.

Concept introduction: The mutated M^L allele is associated with taillessness in Manx cats. The homozygous M^LM^L allele is called as lethal alleles, as they cause death of the kitten as embryo itself due to defects of the spinal cord. Lethal alleles are those in heterozygous or homozygous form that causes death of the individual during embryonic development itself. The probability reduces in such cases, as those alleles will not be transferred to the next generation as the allele is lost with the death of the embryo.

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