Anatomy & Physiology
3rd Edition
ISBN: 9781259398629
Author: McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher: Mcgraw Hill Education,
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Chapter 12.8, Problem 25WDL
Summary Introduction
To determine:
The sequence of events from the arrival of an action potential at the synaptic knob until the release of neurotransmitter into the synaptic cleft.
Concept introduction:
A neurotransmitter is chemical substances which are released by the axon terminals at the time of arrival of the nerve impulses. These neurotransmitters are stored in synaptic vesicles. These vesicles then fuse with the sending membrane which results in the release of neurotransmitter into the synaptic cleft.
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What triggers neurotransmitter release at the synaptic cleft?
Which of the following statements about action potentials and information transmission in the synaptic cleft is FALSE?
1. Action potentials determine the amount of neurotransmitters that are released into the synaptic cleft
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3. Action potentials determine the duration that neurotransmitters are released into the synaptic cleft
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Neurons, particularly those in the brain, receive multiple excitatory and inhibitory signals. What is the name of the extension of the neuron at which such signals are received? How does the neuron integrate these signals to determine whether or not to generate an action potential?
Chapter 12 Solutions
Anatomy & Physiology
Ch. 12.1 - Prob. 1LOCh. 12.1 - Prob. 1WDLCh. 12.1 - Prob. 2LOCh. 12.1 - Prob. 3LOCh. 12.1 - What are the two primary functional divisions of...Ch. 12.1 - Prob. 4LOCh. 12.1 - Prob. 5LOCh. 12.2 - What are the three connective tissue wrappings in...Ch. 12.2 - Prob. 6LOCh. 12.2 - Prob. 4WDL
Ch. 12.2 - Prob. 7LOCh. 12.2 - Prob. 8LOCh. 12.2 - Prob. 5WDLCh. 12.2 - LEARNING OBJECTIVE
9. Distinguish between fast...Ch. 12.2 - Prob. 6WDLCh. 12.2 - Prob. 10LOCh. 12.2 - Prob. 11LOCh. 12.2 - Prob. 7WDLCh. 12.2 - Prob. 8WDLCh. 12.3 - Prob. 12LOCh. 12.3 - Prob. 13LOCh. 12.3 - Prob. 9WDLCh. 12.4 - Prob. 14LOCh. 12.4 - If a person has a brain tumor, is it more likely...Ch. 12.4 - Prob. 15LOCh. 12.4 - Prob. 11WDLCh. 12.4 - Prob. 12WDLCh. 12.4 - Prob. 16LOCh. 12.4 - Prob. 17LOCh. 12.4 - Prob. 13WDLCh. 12.5 - Prob. 18LOCh. 12.5 - Prob. 19LOCh. 12.5 - Prob. 14WDLCh. 12.5 - Prob. 15WDLCh. 12.6 - LEARNING OBJECTIVE
20. Distinguish between a pump...Ch. 12.6 - Prob. 16WDLCh. 12.6 - Prob. 21LOCh. 12.6 - LEARNING OBJECTIVE
22. Identify and describe the...Ch. 12.6 - Prob. 17WDLCh. 12.7 - Prob. 23LOCh. 12.7 - Prob. 18WDLCh. 12.7 - Prob. 24LOCh. 12.7 - Prob. 25LOCh. 12.7 - Prob. 26LOCh. 12.7 - Prob. 19WDLCh. 12.7 - Prob. 20WDLCh. 12.8 - Prob. 27LOCh. 12.8 - LEARNING OBJECTIVE
28. Compare and contrast the...Ch. 12.8 - Prob. 29LOCh. 12.8 - Prob. 1WDTCh. 12.8 - How are EPSP and IPSP graded potentials...Ch. 12.8 - LEARNING OBJECTIVE
30. Define summation, and...Ch. 12.8 - Prob. 22WDLCh. 12.8 - Prob. 31LOCh. 12.8 - Prob. 32LOCh. 12.8 - Prob. 33LOCh. 12.8 - How does depolarization and repolarization occur...Ch. 12.8 - Prob. 24WDLCh. 12.8 - Prob. 34LOCh. 12.8 - Prob. 35LOCh. 12.8 - Prob. 25WDLCh. 12.9 - Prob. 36LOCh. 12.9 - Prob. 26WDLCh. 12.9 - Prob. 37LOCh. 12.9 - Prob. 38LOCh. 12.9 - Prob. 27WDLCh. 12.9 - Prob. 39LOCh. 12.9 - Prob. 28WDLCh. 12.10 - Prob. 40LOCh. 12.10 - Prob. 41LOCh. 12.10 - Prob. 29WDLCh. 12.10 - LEARNING OBJECTIVE
42. Describe how acetylcholine...Ch. 12.10 - Prob. 43LOCh. 12.10 - WHAT DO YOU THINK?
2 Predict the general effect of...Ch. 12.10 - Prob. 30WDLCh. 12.10 - Prob. 44LOCh. 12.10 - Prob. 45LOCh. 12.10 - Prob. 31WDLCh. 12.11 - LEARNING OBJECTIVE
46. Identify the four different...Ch. 12.11 - Prob. 32WDLCh. 12.11 - Prob. 33WDLCh. 12 - _____ 1. The cell body of a neuron does all of the...Ch. 12 - Prob. 2DYBCh. 12 - Prob. 3DYBCh. 12 - Prob. 4DYBCh. 12 - Prob. 5DYBCh. 12 - Prob. 6DYBCh. 12 - _____ 7. An action potential is generated when...Ch. 12 - Prob. 8DYBCh. 12 - Prob. 9DYBCh. 12 - Prob. 10DYBCh. 12 - What are the four structural types of neurons? How...Ch. 12 - Prob. 12DYBCh. 12 - How does myelination differ between the CNS and...Ch. 12 - Describe the procedure by which a PNS axon may...Ch. 12 - Prob. 15DYBCh. 12 - Prob. 16DYBCh. 12 - Explain summation of EPSPs and IPSPs and the...Ch. 12 - Graph and explain the events associated with an...Ch. 12 - Prob. 19DYBCh. 12 - Prob. 20DYBCh. 12 - Prob. 1CALCh. 12 - Prob. 2CALCh. 12 - Prob. 3CALCh. 12 - Prob. 4CALCh. 12 - Sarah wants to call her new friend Julie and needs...Ch. 12 - Over a period of 6 to 9 months, Marianne began to...Ch. 12 - Prob. 2CSLCh. 12 - Prob. 3CSL
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- When an impulse arrives at the synapse, the synaptic vesicles open and release neurotransmitters into the cleft within a thousandth of a second. Within another ten thousandth of a second, these molecules have diffused across the cleft and bound to receptor sites in the effector cell. In what two ways is transmission across a synapse terminated so that the neuron’s signal is concluded?arrow_forwardhow many molecules of neurotransmitter are in a synaptic vesicle?arrow_forwardWhich types of patch clamp technique should be used if you want to determine if a particular compound is influencing synaptic transmission presynaptically or post synaptically?arrow_forward
- Which of the following is the role of axonal Calcium (Ca2+) channels in neuronal communication at the synapse? a) they inhibit the action potential causing it to stop b) Calcium channels have no role in this process c) by allowing calcium to exit the cell, they promote the propagation of action potential across the synapse by creating depolarization d) by blocking calcium entrance, they mediate the contraction of presynaptic axon to facilitate movement e) when they open, calcium enters the presynaptic terminal, promoting fusion of neurotransmitter vesicles with presynaptic membrane, and release of neurotransmitters to the synaptic cleftarrow_forwardIf a pre-synaptic cell releases a large amount of excitatory neurotransmitter into the synaptic cleft, how will that affect the PSPs? Does that large release ensure that the postsynaptic cell will initiate an action potential, and what role does the axon hillock play in this process/decision?arrow_forwardHow can the levels of neurotransmitter in the synaptic cleft be regulated?arrow_forward
- If you increase the amount of neurotransmitter in the synaptic cleft, how would you expect the post-synaptic potential (PSP) to change? a) The PSP would be stronger b) The PSP would change from depolarizing to hyperpolarizing c) The PSP would not changearrow_forwardOrganize the following steps into the correct signal transmission across a synapse. 1. Neurotransmitter molecules diffuse across the synaptic cleft 2. Neurotransmitter molecules bind to postsynaptic neurotransmitter receptors 3. Synaptic vesicles release neurotransmitter molecules 4. Impulse reaches the synaptic knob of the presynaptic neuronarrow_forwardWhy do neurotransmitters have to be removed from the synapse?arrow_forward
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