Essentials of Biology
Essentials of Biology
4th Edition
ISBN: 9780078024221
Author: Sylvia S. Mader Dr., Michael Windelspecht
Publisher: McGraw-Hill Education
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Chapter 12.3, Problem 7A
Summary Introduction

Introduction:

A researcher has cloned a gene for drought resistance in a plant into another species of the plant. This has led to the development of the new hybrid lines of plants. The gene is injected into the parent line and the expression is checked in the next generations of plants after crossing. This procedure is an example of transgenics. The examples include the drought resistant genes, insecticide resistant genes and fungicide resistant genes.

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You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?
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