Essentials of Human Anatomy & Physiology Laboratory Manual (7th Edition)
7th Edition
ISBN: 9780134424835
Author: Elaine N. Marieb, Pamela B. Jackson
Publisher: PEARSON
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Chapter 12, Problem 23SAE
Summary Introduction
To review:
The indispensable role of T-cells (lymphocytes maturing in thymus) in adaptive immunity.
Introduction:
The adaptive immune system has two arms: humoral immunity and cell-mediated immunity. The humoral immunity is controlled by B cells (lymphocytes maturing in the bone marrow), whereas cell-mediated responses are controlled by T cells. Besides that helper T cells (Th Cells) play an indispensable role in adaptive immune responses by activating other cells belonging to the adaptive immune system.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 12 Solutions
Essentials of Human Anatomy & Physiology Laboratory Manual (7th Edition)
Ch. 12 - Prob. 1MCCh. 12 - Prob. 2MCCh. 12 - Prob. 3MCCh. 12 - Which of the following are part of MALT? a....Ch. 12 - 5. Developmentally, embryonic lymphatic vessels...Ch. 12 - 6. Which of the following are among the most...Ch. 12 - Chemical mediators of inflammation include a....Ch. 12 - Against which of the following will interferon do...Ch. 12 - Prob. 9MCCh. 12 - 10. Where exactly does an antigen bind to an...
Ch. 12 - Which of the following antibody capabilities...Ch. 12 - Prob. 12MCCh. 12 - Prob. 13MCCh. 12 - Prob. 14SAECh. 12 - Prob. 15SAECh. 12 - Prob. 16SAECh. 12 - 17. Besides acting as mechanical barriers, the...Ch. 12 - What is complement? Besides bacterial lysis, what...Ch. 12 - 19. Interferons are referred to as antiviral...Ch. 12 - Prob. 20SAECh. 12 - Prob. 21SAECh. 12 - Prob. 22SAECh. 12 - Prob. 23SAECh. 12 - Prob. 24SAECh. 12 - Binding of antigens to receptors of...Ch. 12 - Prob. 26SAECh. 12 - Prob. 27SAECh. 12 - 28. Compare and contrast a primary and a secondary...Ch. 12 - Prob. 29SAECh. 12 - Prob. 30SAECh. 12 - Prob. 31SAECh. 12 - Distinguish between immediate types of allergy and...Ch. 12 - Prob. 33SAECh. 12 - Prob. 34SAECh. 12 - Contrast lysozyme, perforin and granzymes, and a...Ch. 12 - Prob. 36CTCh. 12 - Prob. 37CTCh. 12 - Prob. 38CTCh. 12 - Mrs. Morrow, a 59-year-old woman, has undergone a...Ch. 12 - 40. Lymphocytes continuously circulate through the...Ch. 12 - Capillary permeability increase and plasma...
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