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Chapter 12, Problem 18P

(a)

Summary Introduction

To propose:

A reasonable model to explain that exposing a sensory neuron containing TRPV1 to high temperature leads to a sensation of heat.

Introduction:

Neuron is also known as nerve cell is defines as the cell that carries electrical impulses. It serves as the basic unit of nervous system. It is composed of axon, cell body and dendrites.

(b)

Summary Introduction

To explain:

The few drops of hot peper sauce can taste very hot without actually burning you.

Introduction:

Capsaicin is defined as an active compound of chili peppers produced by plants of genus Capsicum. It is irritant for mammals including humans as it produces a burning sensation in tissues when it comes in contact.

(c)

Summary Introduction

To determine:

The sensations produced from contact with low and high levels of menthol.

Introduction:

Menthol is an organic compound which is obtained from corn mint, peppermint or other mint oils. TRPM8 is a transient receptor potential cation channel belongs to M member 8 is a type of proteins which is encoded by TRPM8 gene. It is molecular transducer of cold somatosensation in humans.

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