BIO 117/118-LAB MANUAL>CUSTOM<
BIO 117/118-LAB MANUAL>CUSTOM<
15th Edition
ISBN: 9781307026757
Author: Mader
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Chapter 11.3, Problem 1LO
Summary Introduction

To write:

A major organ found in each organ system.

Introduction:

There are majorly 11 organ systems in our body. They are:

1) Digestive system- Major organ is stomach.

2) Respiratory system- Major organ is lungs.

3) Circulatory system- Major organ is the heart.

4) Reproductive system- Major organ in males is testes and in females is ovary.

5) Excretory system - Major organ is the kidney.

6) Nervous system- Major organ is the brain.

7) Endocrine system- Major organ is the hypothalamus as it controls other endocrine glands.

8) Integumentary system- Major organ is the skin.

9) Skeletal system- Major organ is bones.

10) Muscular system- Major organ is muscles.

11) Lymphatic system- Major organ is spleen.

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Digoxin: Intravenous Bolus - Two Compartment Model Drug Digoxin Route: IV Bolus Dose: 0.750 mg Plasma Concentration Time Profile Beta Alpha Time (hrs) Conc (ng/ml) LN (ng/ml) LN (ng/ml) LN 0.00 #NUM! #NUM! #NUM! 0.10 12.290 2.509 #NUM! #NUMI 0.60 6.975 1.942 #NUM! #NUMI 1.00 4.649 1.537 #NUM! #NUMI 2.00 2.201 0.789 #NUM! #NUM! 3.00 1.536 0.429 #NUM! #NUM! 4.00 1.342 0.294 #NUM! #NUM! 5.00 1.273 0.241 #NUM! #NUMI 6.00 1.238 0.213 #NUM! #NUM! 7.00 1.212 0.192 #NUM! #NUM! 8.00 1.188 0.172 #NUMI #NUM! 9.00 1.165 0.153 #NUM! #NUMI 10.00 1.143 0.134 #NUMI #NUM! 11.00 1.122 0.115 #NUM! 12.00 1.101 0.096 #NUMI 13.00 1.080 0.077 #NUMI 16.00 1.020 0.020 #NUMI 24.00 0.876 -0.132 #NUMI Pharmacokinetic Parameters Parameter Value Alpha B Beta Units ng/ml hr-1 ng/ml hr-1 CO ng/ml H.C AUC ng x hr/ml Vc Vbeta Vss C L/hr TK (alpha) hr TX (beta) days 5+ F3 F4 F5 0+ F6 F7 % 6 95 14 #3 29 & t F8 F9 FW EW
Linuron, a derivative of urea, is used as an herbicide. Linuron serum levels were measured in 4Kg rabbits following a bolus IV injection of 10mg/kg. Time (minutes) Serum Linuron Levels (ug/ml) following IV dose 10 15.48 20 8.60 30 5.90 45 3.78 60 2.42 90 1.49 120 0.93 180 0.60 240 0.41 300 0.29 360 0.22 Analyze this data and perform the necessary calculations to determine the following pharmacokinetic parameters from the IV data: (5 points per parameter, 24 parameters/variables ■ 120 points possible). You do NOT need to submit graphs or data tables. Give the terminal regression line equation and R or R² value: Give the x axis (name and units, if any) of the terminal line: Give the y axis (name and units, if any) of the terminal line: Give the residual regression line equation and R or R² value: Give the x axis (name and units, if any) of the residual line: Give the y axis (name and units, if any) of the residual line:

Chapter 11 Solutions

BIO 117/118-LAB MANUAL>CUSTOM<

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12 Organ Systems | Roles & functions | Easy science lesson; Author: Learn Easy Science;https://www.youtube.com/watch?v=cQIU0yJ8RBg;License: Standard youtube license