Campbell Biology In Focus
2nd Edition
ISBN: 9780134203072
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece
Publisher: PEARSON
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Chapter 11, Problem 9TYU
Summary Introduction
To determine:
The probability of the offspring of Karen and Steveto have sickle cell anemia, if both of them have siblings who had sickle cell anemia.
Introduction:
Sickle cell anemia is a disease in which the red blood corpuscles are sickle shaped or crescent shapedrather than round with a grove in the middle. This is caused due to a mutation in one of the base pairs and it is a hereditary disease. It causes the loss in binding of oxygen molecule to red blood cells.
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Imagine that you are a clinical geneticist. Your colleague is an oncologist who wants your help explaining the basics of genetics to their patient, who will be undergoing genetic testing in the coming weeks for possible acute myeloid leukemia (AML) induced by the radiation she had several years ago for breast cancer.
Write a 1,050- to 1,225-word memo to your colleague.
Include the following in your memo:
An explanation of the molecular structure of DNA and RNA, highlighting both similarities and differences
A description of the processes of transcription and translation
An explanation of the differences between leading and lagging strands and how the DNA is replicated in each strand
Reponses to the following common questions patients might ask about this type of genetic testing and genetic disorder:
Does AML run in families?
What genes are tested for?
Respond to the following in a minimum of 175 words:
What are some potential consequences that could result if the processes of replication, transcription, and translation don’t function correctly?
Provide an example of how you might explain these consequences in terms that patients might understand.
Chapter 11 Solutions
Campbell Biology In Focus
Ch. 11.1 - DRAW IT Pea plants heterozygous for flower...Ch. 11.1 - List all gametes that could be made by a pea plant...Ch. 11.1 - Prob. 3CCCh. 11.2 - For any gene with a dominant allele A and...Ch. 11.2 - Two organisms, with genotypes BbDD and BBDd, are...Ch. 11.2 - Prob. 3CCCh. 11.3 - Incomplete dominance and epistasis are both terms...Ch. 11.3 - Prob. 2CCCh. 11.3 - WHAT IF? A rooster with gray feathers and a hen of...Ch. 11.4 - Beth and Tom each have a sibling with cystic...
Ch. 11.4 - MAKE CONNECTIONS In Table 11.1, note the...Ch. 11 - DRAW IT Two pea plants heterozygous for the...Ch. 11 - A man with type A blood marries a woman with type...Ch. 11 - A man has six fingers on each hand and six toes on...Ch. 11 - Prob. 4TYUCh. 11 - Flower position, stem length, and seed shape are...Ch. 11 - Prob. 6TYUCh. 11 - Prob. 7TYUCh. 11 - Prob. 8TYUCh. 11 - Prob. 9TYUCh. 11 - Prob. 10TYUCh. 11 - In tigers, a recessive allele that is pleiotropic...Ch. 11 - Prob. 12TYUCh. 11 - Imagine that you are a genetic counselor, and a...Ch. 11 - Prob. 15TYUCh. 11 - Prob. 16TYUCh. 11 - Prob. 17TYU
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