FUNDAMENTALS OF BIOCHEMISTRY WPNG 1-SEME
5th Edition
ISBN: 9781119750192
Author: Voet
Publisher: WILEY
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Chapter 11, Problem 15E
Summary Introduction
To explain: The reason behind the lysozyme that cleaves the artificial substrate (NAG)4~4000 times more slowly than it cleaves (NAG)6.
Concept introduction: Lysozyme is an antimicrobial enzyme that forms a part of the innate immune system. Lysozyme attacks the protective cell walls of bacteria. It increases a healthy shelf life and ensures food safety.
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approximated as carbon spheres of radius r = 1 mm, are
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Chapter 11 Solutions
FUNDAMENTALS OF BIOCHEMISTRY WPNG 1-SEME
Ch. 11 - Prob. 1ECh. 11 - 2. What is the relationship between the rate of an...Ch. 11 - 3. Which type of enzyme (Table 11-2) catalyzes the...Ch. 11 - 4. Which type of enzyme (Table 11-2) catalyzes the...Ch. 11 - 5. On the free energy diagram shown, label the...Ch. 11 - Prob. 6ECh. 11 - 7. Approximately how much does staphylococcal...Ch. 11 - 8. Calculate the rate enhancement that could be...Ch. 11 - 9. Explain why enzyme activity varies with...Ch. 11 - 10. The covalent catalytic mechanism of an enzyme...
Ch. 11 - Prob. 11ECh. 11 - 12. Explain why RNase A cannot catalyze the...Ch. 11 - 13. Urease, the first enzyme to be crystallized,...Ch. 11 - 14. Wolfenden has stated that it is meaningless to...Ch. 11 - 15. Explain why lysozyme cleaves the artificial...Ch. 11 - 16. Would you expect lysozyme to hydrolyze...Ch. 11 - 17. Design a chloromethylketone inhibitor of...Ch. 11 - 18. Predict the effect of mutating Asp 102 of...Ch. 11 - 19. Diagram the hydrogen-bonding interactions of...Ch. 11 - Prob. 20ECh. 11 - 21. Using the reaction shown in Box 11-1 (the...Ch. 11 - Prob. 22CQCh. 11 - 23. What feature of RNA would allow it to function...Ch. 11 - 24. Suggest a transition state analog for proline...Ch. 11 - 25. Lysozyme residues Asp 101 and Arg 114 are...Ch. 11 - 26. Predict the effect on lysozyme’s activity of...Ch. 11 - Prob. 27CQCh. 11 - Prob. 28CQCh. 11 - Prob. 29CQCh. 11 - 30. Many of the cell’s hydrolytic enzymes are...Ch. 11 - Prob. 31CQCh. 11 - Prob. 32CQCh. 11 - Prob. 1MTE
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