Considering signal processing in multicellular organisms, determine the mechanism by which pheromone signal in yeast is further processed in the cell to trigger the cell response. Introduction: When a pheromone binds to the receptor in the cell, it phosphorylates the peripheral membrane protein related to Ras. This activates the mitogen-activated protein kinase (MAPK), which phosphorylates and further activates second and third MAPKs in a sequence. Other proteins are activated by the third MAPK, which triggers a cell response. Instead of involving the production of secondary messengers, the pheromone-activated response in yeast involves a peripheral membrane protein related to Ras.

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Chapter 11, Problem 12PIAT

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Considering signal processing in multicellular organisms, determine the mechanism by which pheromone signal in yeast is further processed in the cell to trigger the cell response.

Introduction:

When a pheromone binds to the receptor in the cell, it phosphorylates the peripheral membrane protein related to Ras. This activates the mitogen-activated protein kinase (MAPK), which phosphorylates and further activates second and third MAPKs in a sequence. Other proteins are activated by the third MAPK, which triggers a cell response. Instead of involving the production of secondary messengers, the pheromone-activated response in yeast involves a peripheral membrane protein related to Ras.

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