Campbell Biology: Concepts & Connections, Books a la Carte Plus Mastering Biology with eText -- Access Card Package (8th Edition)
8th Edition
ISBN: 9780133909029
Author: Jane B. Reece, Martha R. Taylor, Eric J. Simon, Jean L. Dickey, Kelly A. Hogan
Publisher: PEARSON
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Chapter 11, Problem 10TYK
A mutation in a single gene may cause a major change in the body of a fruit fly, such as an extra pair of legs or wings. Yet it probably takes the combined action of hundreds or thousands of genes to produce a wing or leg. How can a change in just one gene cause such a big change in the body?
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One unexpected result of the sequencing of the human genome was the finding that mutations in a single gene can be responsible for multiple distinct disorders. How do you think mutations in a single gene can have such diverse effects?
Gene mutations can be classified in two major ways:(1) hereditary or germline mutations that are inherited from a parent and are present throughout a person’s life in virtually every cell in the body.(2) acquired or somatic mutations that occur at some time during a person’s life and are present only in certain cells, not in every cell in the body.If there is no family history of a particular disease but a child has the disease then it may have arisen due to a(n) ________ mutation early during development.
A) acquired
B) inherited
C) silent
D) transition
You are working in a lab that studies stickleback fish. These fish normally have three spines that occur on the back of the stickleback. One day you notice that a young stickleback has no spines on its back but instead has three spines growing out of the top of its head! (answer both questions)
question 1: A mutation in what type of gene is probably the cause of this unusual situation? Why?
question #2: would you expect the proteins that make the spines to be different in the mutant fish compared to a wildtype fish. Why or why not?
Chapter 11 Solutions
Campbell Biology: Concepts & Connections, Books a la Carte Plus Mastering Biology with eText -- Access Card Package (8th Edition)
Ch. 11 - Complete the following concept map to test your...Ch. 11 - Level 1: Knowledge/Comprehension 2. Which of the...Ch. 11 - A homeotic gene does which of the following? a. It...Ch. 11 - Which of the following is a valid difference...Ch. 11 - The control of gene expression is more complex in...Ch. 11 - Your bone cells, muscle cells, and skin cells look...Ch. 11 - Prob. 7TYKCh. 11 - You obtain an egg cell from the ovary of a white...Ch. 11 - Mutations can alter the function of the lac operon...Ch. 11 - A mutation in a single gene may cause a major...
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- One unexpected result of the sequencing of the human genome was the finding that mutations in a single gene can be responsible for multiple distinct disorders. For example, mutations in the RET gene can cause two different types of multiple endocrine neoplasias, familial medullary thyroid carcinoma, and Hirschsprung disease. How do you think mutations in a single gene can have such diverse effects?arrow_forwardIf you have a mutation in your skin cells from falling asleep in a tanning bed, how will this affect your offspring? Question 10 options: It will affect their entire body because their entire body grew out of the fertilized egg It may affect them, depending on whether those particular skin cells are passed on to them It will affect your offspring's skin cells only It won't affect them because the mutation is not in a gamete It won't affect them because mutations cannot be passed down to offspringarrow_forwardOriginal DNA Sequence: TACAC CTTGG CGACGACT... MRNA Sequence: Amino Acid Sequence: Mutated DNA Sequence #5 TACACCTT G G GACGACT... (Highlight the change) What's the mRNA sequence? What will be the amino acid sequence? Will there likely be effects? What type of mutation is this? 1. Which type of mutation is responsible for new variations of a trait? 2. Which type of mutation does not result in an abnormal amino acid sequence? 3. Which type of mutation stops the translation of an mRNA molecule? NOarrow_forward
- I believe that there are many good things that can come out of people getting to design their baby’s genetic material. But there are also many bad things as well. From the article by Bio medical about the pros and cons of having a designer baby it states that a pro is that this type of engineering can “ might help prevent genetic diseases such as Alzheimer’s, Huntington’s Disease, down syndrome, Spinal Muscular Atrophy, and many others”. I think that it is great that we could get rid of Alzheimer’s due to how destructive it can be to the people that suffer it. But I think the other diseases that it can eliminate is horrible due to them making our world a more unique place such as people with autism, Down syndrome. By doing this it could eliminate the whole population of people with disabilities community and make everyone “normal”. Another bad that I found in the article Ethics of designer babies which states that a major flaw for these babies is “designer baby technologies suggest…arrow_forwardAlthough it is well known that X-rays cause mutations, they are routinely used to diagnose medical problems, including potential tumors, broken bones, and dental cavities. So why do we still use X-rays in medicine anyway? What precautions need to be taken?arrow_forwardMutagens, when introduced to the body can always cause cancer. Is this statement true? Select the correct response: No. Mutagens do not necessarily, directly equate to the cause of cancer. A cancer is usually caused by a substance called carcinogen that increases the probability of inducing a tumor. Mutagens can be limited to the result of spontaneous or induced mutations that causes changes and/or errors in the coding and reading of the DNA strand and in the genetic make- up of the organism involved. Though some mutagens are considered as carcinogens, not all mutagens can lead to cancer. Yes. The terms can be used interchangeably even in the medical field. Yes. Mutagens does equate to the cause of cancer. A cancer is usually caused by a substance called carcinogen that increases the probability of inducing a tumor. However, mutagens is not only limited to the result of spontaneous or induced mutations that causes changes and/or errors in the coding and reading of the DNA strand and in…arrow_forward
- Sickle cell anemia is a disease caused by a mutation at the genotypic level. A person with two copies of the gene has the disease, but a person with one copy of the gene does not have the disease. The diagram shows how this mutation affects an organism. Use the image to answer the question. The mutation causes the deformity of the red blood cell, the component of blood that carries oxygen throughout the body. The deformed cells can clump together and can clog blood vessels. The parasites responsible for the sickle cell condition are killed in the deformed red blood cells. In which type of environment would carriers of the disease be naturally selected for? A. low altitude B. high altitude C. low population of parasites D. high population of parasitesarrow_forwardIn an epic battle, the Green Goblin was able to wound Spider-Man and collect a sample of his cells. Utilizing a HuMouse model organism, the Goblin got the mutated chromosomes into the animals and began breeding them to determine the basis of their chromosomal inheritance. In the process of conducting his research, he discovered the gene associated with spider-like powers are actually three distinct genes: one for spider sense; one for super strength; one for enhanced agility. All genes appear to be dominant, so the Goblin runs a test cross and gets the following results: Phenotype Agility Number of Progeny 94 Agility and Sense 3 All 3 Powers 580 Sense 40 Strength and Agility Strength and Sense Strength 45 89 5 No Powers 592 What is the map distance between Strength and Agility genes? (Enter your number as map units, or centiMorgans, but without units)arrow_forwardThe table below shows different types of mutations in different positions in four genes. Choose the letter (A to E), from the drop-down menu, that represents the most likely type of protein that will be produced from each of these mutated genes. A: completely normal protein B: functional protein with ONE amino acid different from normal C: non-functional protein with ONE amino acid different from normal D: non-functional protein with MANY amino acids different from normal E: no protein at all Answer Type of mutation Position of mutation in gene (A, B, C, D, or E) before the part of the gene that specifies the active site of the enzyme 2 base pair insertion Inonsense immediately before the stop codon in the part of the gene that specifies the active site of the enzyme silent 1 base pair insertion in an intronarrow_forward
- You are working in a lab that studies stickleback fish. These fish normally have three spines that occur on the back of the stickleback. One day you notice that a young stickleback has no spines on its back but instead has three spines growing out of the top of its head! Question: Briefly explain a study you could do to test if the difference between the mutant and wild type fish was due to a difference in the structural gene that makes the spines or due to a difference in gene expression.arrow_forwardBeing able to understand the relationship between DNA, mRNA, tRNA, ribosomes and proteins, is necessary for any researcher interested in gene therapy. Gene therapy is dedicated to correcting genetic defects by replacing mutated genes with wildtype versions. This can include complete removal and introduction of a working copy of the entire gene (using knock-outs and knock-ins) or removal of only the actual mutated nucleotide. Sickle Cell Disease is an example of a recessive disorder based on a single-point mutation: GAG becomes GTG, which encodes a new amino acid. One would only need to replace a single base to correct the disorder making it very attractive to gene therapy researchers. The mutant sickle cell allele is called HbS (for sickled hemoglobin) while the wt allele is HbA. Pretend that Arcel Kasongo, a masters student from Cambridge, is studying for an oral exam on gene therapy, and has an especial interest in the disorder since he comes from the Democratic Republic of Congo…arrow_forwardBeing able to understand the relationship between DNA, mRNA, tRNA, ribosomes and proteins, is necessary for any researcher interested in gene therapy. Gene therapy is dedicated to correcting genetic defects by replacing mutated genes with wildtype versions. This can include complete removal and introduction of a working copy of the entire gene (using knock-outs and knock-ins) or removal of only the actual mutated nucleotide. Sickle Cell Disease is an example of a recessive disorder based on a single-point mutation: GAG becomes GTG, which encodes a new amino acid. One would only need to replace a single base to correct the disorder making it very attractive to gene therapy researchers. The mutant sickle cell allele is called HbS (for sickled hemoglobin) while the wt allele is HbA. Pretend that Arcel Kasongo, a masters student from Cambridge, is studying for an oral exam on gene therapy, and has an especial interest in the disorder since he comes from the Democratic Republic of Congo…arrow_forward
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