Explanation Phenylketonuria, a genetic disorder, is inherited from parents to their offsprings. This disease causes synthesis of a defective enzyme which affects phenylalanine metabolism. Phenylalanine metabolism is essential for the synthesis of tyrosine which is a non-essential amino acid in a healthy individual. Amino acids that are synthesized in the body itself are called non-essential amino acids, such as serine, alanine, arginine, tyrosine and many more. Amino acids that are required to be taken from diet are called essential amino acids, such as valine, leucine, isoleucine, methionine, and many more...

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN: 9781305251052

Author: Michael Cummings

Publisher: Cengage Learning

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Question

Chapter 10.4, Problem 1GR

Summary Introduction

To explain: Whether the amino acid tyrosine is an essential amino acid in individuals suffering with PKU..

Introduction: Phenylketonuria (PKU) is a genetic disorder that is inherited from one generation into the next. PKU is caused because of the mutation in the gene that codes for the enzyme required for metabolism of phenylalanine. This mutation causes synthesis of the defective enzyme and thus, proper metabolism of phenylalanine is not achieved.

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Chapter 9, Problem 24QP

Chapter 10.4, Problem 2GR

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Individuals with phenylketonuria cannot convert phenylalanine to tyrosine. Why don’t these individuals exhibit a deficiency of tyrosine?

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Chapter 10 Solutions

Human Heredity: Principles and Issues (MindTap Course List)

Ch. 10.4 - Prob. 1GR Ch. 10.4 - Prob. 2GR Ch. 10.7 - Prob. 1EG Ch. 10.7 - Prob. 2EG Ch. 10 - A couple was referred for genetic counseling...Ch. 10 - A couple was referred for genetic counseling...Ch. 10 - A couple was referred for genetic counseling...Ch. 10 - Many individuals with metabolic diseases are...Ch. 10 - Prob. 2QP Ch. 10 - Enzymes have all the following characteristics...

Ch. 10 - Questions 4 through 6 refer to the following...Ch. 10 - Questions 4 through 6 refer to the following...Ch. 10 - Prob. 6QP Ch. 10 - Prob. 7QP Ch. 10 - Prob. 8QP Ch. 10 - a. Compounds A, B, C, and D are known to be...Ch. 10 - b. Compounds A, B, C, and D are known to be...Ch. 10 - a. If an individual who is homozygous for the...Ch. 10 - Prob. 12QP Ch. 10 - Suppose that in the formation of phenylalanine...Ch. 10 - If phenylalanine was not an essential amino acid,...Ch. 10 - Phenylketonuria and alkaptonuria are both...Ch. 10 - The normal enzyme required for converting sugars...Ch. 10 - Knowing that individuals who are homozygous for...Ch. 10 - Prob. 18QP Ch. 10 - A person was found to have very low levels of...Ch. 10 - If an extra nucleotide is inserted in the first...Ch. 10 - Transcriptional regulators are proteins that bind...Ch. 10 - Prob. 22QP Ch. 10 - Prob. 23QP

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Solution Summary: The author explains that tyrosine is an essential amino acid in people suffering from phenylketonuria.

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