Essentials of Genetics (9th Edition) - Standalone book
Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 10, Problem 4CS
Summary Introduction

To review:

The involvement of RNA (ribonucleic acid) component of telomerase causing dyskeratosis congenita (DKC) as a result of mutation.

Introduction:

Telomerase is a remarkable enzyme that replicates the telomere region of the eukaryotic chromosome. It includes many protein subunits as well as an RNA component called telomerase RNA component (TERC). Dyskeratosis congenita is a rare genetic disorder, which causes prematureaging in the affected individuals. The symptoms for DKCstart appearing between the age of 5 and 15 years. People with DKC have shorter life expectancy but many live till the age of 60 years.

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