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Chapter 1, Problem 6CT
Summary Introduction

To answer:

How an epidemiologist proves or disproves the claim (cholera resulted from the nocturnal clouds of vapor from the Thames River).

Introduction:

During the 19th century, London (Soho district) faced a serious cholera outbreak from improper services over sanitary conditions. The Soho-draining system upheld the rotting fluids, animal droppings, grease-boiling dens, and the slaughterhouse below their floorboards (cesspools and cellars). Due to the leak of cesspools and the cellars, the London government decided to dump these wastes in the Thames River. This leads to contamination of the water.

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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.  b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake? Options: A. Dose; Increase dose     B. Dose; Decrease dose     C. Dose; Do not change dose     D. Interval; Increase the interval between doses (give the drug less frequently)    E. Interval; Decrease the interval between doses (give the drug more frequently)     F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math

Chapter 1 Solutions

Microbiology with Diseases by Body System & Modified MasteringMicrobiology with Pearson eText -- ValuePack Access Card -- for Microbiology with Diseases by Body System Package

Ch. 1 - Prob. 6MCCh. 1 - Prob. 7MCCh. 1 - Prob. 8MCCh. 1 - A scientist who studies the role of microorganisms...Ch. 1 - The laboratory of Robert Koch contributed which of...Ch. 1 - Fill in the Blanks 1. Environmental microbiology...Ch. 1 - Prob. 2FIBCh. 1 - Fill in the Blanks 3. Chemotherapy _______________Ch. 1 - Fill in the Blanks 4. Immunology _______________Ch. 1 - Fill in the Blanks 5. Infection control...Ch. 1 - Fill in the Blanks 6. Etiology _______________Ch. 1 - Fill in the Blanks 7. Epidemiology _______________Ch. 1 - Fill in the Blanks 8. Biotechnology...Ch. 1 - Fill in the Blanks 9. Food microbiology...Ch. 1 - Why was the theory of spontaneous generation a...Ch. 1 - Discuss the significant difference between the...Ch. 1 - List six types of microorganisms.Ch. 1 - Defend this statement: The investigations of...Ch. 1 - Why would a macroscopic tapeworm be studied in...Ch. 1 - Describe what has been called the Golden Age of...Ch. 1 - List four major questions that drive...Ch. 1 - Refer to the four steps in the scientific method...Ch. 1 - Prob. 9SACh. 1 - What does the term HAI (nosocomial infection) have...Ch. 1 - Match each of the following descriptions with the...Ch. 1 - Prob. 1VICh. 1 - Show where microbes ended up in Pasteurs...Ch. 1 - If Robert Koch had become interested in a viral...Ch. 1 - In 1911, the Polish scientist Casimir Funk...Ch. 1 - Haemophilus influenzae does not cause flu, but it...Ch. 1 - Just before winter break in early December, your...Ch. 1 - Design an experiment to prove that microbes do not...Ch. 1 - Prob. 6CTCh. 1 - Compare and contrast the investigations of Redi,...Ch. 1 - If you were a career counselor directing a student...Ch. 1 - A few bacteria produce disease because they derive...Ch. 1 - How might the debate over spontaneous generation...Ch. 1 - French microbiologists, led by Pasteur, tried to...Ch. 1 - Why arent Kochs postulates always useful in...Ch. 1 - Albert Kluyver said, From elephant to ......Ch. 1 - The ability of farmers around the world to produce...Ch. 1 - Prob. 1CM
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