INTRO TO GEN ANALYSIS W/ACHIEVE ACCESS
INTRO TO GEN ANALYSIS W/ACHIEVE ACCESS
12th Edition
ISBN: 9781319423865
Author: Griffiths
Publisher: MAC HIGHER
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Chapter 1, Problem 16P

a.

Summary Introduction

To determine: The maximum amount of mutation that can be seen in the male chromosomes.

Introduction: The two types of sexes, males and females possess different sexual characteristics due to the presence of their sexual hormones along with the different sex chromosomes. The male shows heterogamety, whereas the female shows homogametic nature.

b.

Summary Introduction

To determine: The least number of mutations on which chromosome.

Introduction: The cells that are to be inherited undergo the process of meiosis in which there occurs the reduction of chromosome number to half.

c.

Summary Introduction

To determine: The new mutation rate per base pair on the X and Y chromosome.

Introduction: The male possesses the heterogametic nature, whereas the females possess the homogametic nature. Males have X and Y chromosomes, whereas females have a pair of X chromosomes.

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*Example 2: Tracing the path of an autosomal dominant trait Trait: Neurofibromatosis Forms of the trait: The dominant form is neurofibromatosis, caused by the production of an abnormal form of the protein neurofibromin. Affected individuals show spots of abnormal skin pigmentation and non-cancerous tumors that can interfere with the nervous system and cause blindness. Some tumors can convert to a cancerous form. i The recessive form is a normal protein - in other words, no neurofibromatosis.moovi A typical pedigree for a family that carries neurofibromatosis is shown below. Note that carriers are not indicated with half-colored shapes in this chart. Use the letter "N" to indicate the dominant neurofibromatosis allele, and the letter "n" for the normal allele. Nn nn nn 2 nn Nn A 3 N-
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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY