Why might you expect a small dose of puromycin to be less effective in repressing bacterial growth than an equivalent number of mole- cules of erythromycin?
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- An injection contains 5 million international units (MIU) of interferon alpha-n3 (ALFERON N) proteins per milliliter. The recommended dose is 0.05 mL. The literature states that the activity of interferon alpha-n3 is approximately equal to 2.6 × 108international units/mg of protein. Calculate (a) the number of international units and (b) the micrograms of interferon alfa-n3 proteins administered per dose.How do you think a bacterial cell would respond if it was treated with the antibiotic vancomycin compared to the antibiotic erythromycin? Note: this question is asking about the bacterial response, not the specific action of the antibiotic, although you need to know this to answer the question.In (b), why would it be more efficient to use labeled anti-human IgG rather than label the patient’s antibodies?
- Before development of a vaccine against this microbe, thedisease it caused accounted for two-thirds of bacterial meningi-tis cases during the first year of life but is still the number oneleading cause of mental retardation in patients who survive seri-ous disease due to permanent central nervous system disorders.What is the microorganism?(a) Haemophilus influenzae type B(b) Haemophilus influenzae type A(c) Neisseria meningitidis(d) Streptococcus pneumoniae(e) Listeria monocytogenesCan a mouse infected with Bacillus anthracis generate antibodies against the S-layer? How do you know? I need help finding the answer in the article and explain in short answer link to article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC106848/Microtubule stabilisers may be used as anticanceragents. Propose a set of four molecules from the literature that can be overlaid to give a commonpharmacophore. Label the key structural featuresthat indicate some similarity between themolecules.
- Antibiotic resistance can be transferred from one bacterial cell to another. Describe how this process can occur.Mangaba, the laboratory technician, is interested in determining narcotics in saliva at this concentrations > 10 mg/L (μg/mL). One approach being considered is to use an immunochemical assay. Which immunoassay would be most suitable for the desired assay? Explain. Describe the immunoassays that are sensitive enough to measure as little as 10 mg/L of antigen? Which of these assays can quantitate urine albumin? Which of these assays are technically complex or require dedicated, expensive instrumentation?Palivizumab is a humanized monoclonal anitbody for the prohylaxis of resporatory diseases caused by respiratory syncytical virus (RSV) Researches added palivizumab ( or anitbody 101F as positive control) to RSV prior to incubation with human cells. Based on what you learned about palivizumab what does the data recorded below demonstrate about palivizumab mechanism of action?
- As a research scientist working on MS detail the possible strategic directions you could take to produce and purify large quantities of the human interferon β-1b. choose which strategy you think the team should take and why.A bacterium can protect itself against antibiotics in different ways. Describe 4 fundamentally differentmechanisms of antibiotic resistance. Discuss whether there are any basicdifferences or similarities between these 4 mechanisms and, if so, describe them.The production of antimicrobial peptides is one of the most evolutionarily ancient mechanisms of defense for multicellular organisms, and most eukaryotic species make many different forms of these proteins. For instance, human paneth cells in the gastrointestinal epithelium make 21 different defensins. The reason for this diversity of antimicrobial peptides is: Epithelial cells make different forms than those made by neutrophils. Neutrophils make many different defensins and store them as inactive proteins in their secretory granules. Most of them are produced only in response to infection. The production of different peptides is induced following a bacterial infection versus a fungal infection. Each one has distinct activities against Gram-negative bacteria, Gram-positive bacteria, or fungi.