Why is the use of auxotrophy not a good method for controllingthe growth of a genetically modified organism?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Why is the use of auxotrophy not a good method for controlling
the growth of a genetically modified organism?

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Genetically modified organisms are those living organisms which have been genetically modified by inducing mutation in the genome hence resulting in then change of the genetic makeup in order to form something new.

Auxotrophy is the inability of the organism to synthesize biomolecules which are essential for its growth. The organisms which show auxotrophy are called auxotrophic. The genetically modified organisms are made auxotrophic in order to maintain their growth rate and keep them in bio containment. The GMOs are unable to synthesize growth promoting molecules due to mutation therefore, those molecules are provided externally in the containment area to maintain the development.

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