Why is the net charge 0 for cooh? Shouldn't it be +1?

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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Why is the net charge 0 for cooh? Shouldn't it be +1?

Glutamate, Glu, E
H
HƠN - C co
T
CH₂
pha 4,5
PH 2.1 +NH3 +1
4.1 *NH3
+1
CH₂
4,5 ENH2JINH 23 H2 có
-
pka 4.1
PH 2.1 COOH
4.1 [co] = [CODA] -1/2
9.5 CDD
Overall charge pH 2.3 +1/2
2
4.1
-1/₂ >
9.5 - 11/2
5
N
3
pka 2.1
at PH 2.1 [co] = [cook] - 1/₂
4.1
Coo
-1
9.5
4
All
)?
PI = 2₁1 + 4.1 = 3.1
2
COO
8
Sep 16
1:26 +
Transcribed Image Text:Glutamate, Glu, E H HƠN - C co T CH₂ pha 4,5 PH 2.1 +NH3 +1 4.1 *NH3 +1 CH₂ 4,5 ENH2JINH 23 H2 có - pka 4.1 PH 2.1 COOH 4.1 [co] = [CODA] -1/2 9.5 CDD Overall charge pH 2.3 +1/2 2 4.1 -1/₂ > 9.5 - 11/2 5 N 3 pka 2.1 at PH 2.1 [co] = [cook] - 1/₂ 4.1 Coo -1 9.5 4 All )? PI = 2₁1 + 4.1 = 3.1 2 COO 8 Sep 16 1:26 +
Expert Solution
Step 1: Glutamate

Amino acids are biomolecules that have an amino group, a carboxyl group and a side group that is linked to the same carbon. The amino group and carboxyl group of all amino acids are ionisable but the side group may or may not be ionisable. 

Glutamate is an acidic amino acid. It has a secondary carboxyl group in its side group. 

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