While discussing the SN1 mechanism, we learned that H2O is an extremely weak nucleophile. So weak that it CANNOT perform an SN2 mechanism. Analyze the properties of the oxygen atom in H20, since the oxygen is the atom that attacks in an SN1 mechanism. Which nucleophiles listed below share similarities to H20 and would be expected to be very weak nucleophiles as well? Choose- all that apply. LIOCH2CH2CH3 HOCH3 NaOH HOCH2CH2CH3 CH3CO2NA (a carboxylate) CH3CO2H (a carboxylic acid)

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Designing a Synthesis

Organic synthesis is a branch of chemical synthesis that involves the planned construction of organic compounds/molecules from smaller units that possess functional groups. Friedrich Wöhler was the first scientist who designed the synthesis of an organic compound, urea from inorganic starting materials silver cyanate with ammonium chloride via a simple, one-step synthesis.